U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    AGD7 ARF-GAP domain 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818331, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    AGD7
    Official Full Name
    ARF-GAP domain 7
    Primary source
    TAIR:AT2G37550
    Locus tag
    AT2G37550
    See related
    Araport:AT2G37550
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARF-GAP domain 7; ASP1; F13M22.5; F13M22_5; yeast pde1 suppressor 1
    Summary
    A member of ARF GAP domain (AGD), A thaliana has 15 members, grouped into four classes.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See AGD7 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (15755078..15757601, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger domain-containing protein Neighboring gene forkhead box protein G1 Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene ncRNA Neighboring gene origin recognition complex second largest subunit 2 Neighboring gene HSP20-like chaperones superfamily protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Overexpression of Arabidopsis AGD7 causes relocation of Golgi-localized proteins to the endoplasmic reticulum and inhibits protein trafficking in plant cells. Min MK, et al. Plant Physiol, 2007 Apr. PMID 17307897, Free PMC Article
    2. Protein and metabolite composition of Arabidopsis stress granules. Kosmacz M, et al. New Phytol, 2019 May. PMID 30664249
    3. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
    4. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_001036426.1
    NM_129310.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    ARF-GAP domain 7
    NP_001031503.1
    • ARF-GAP domain 7 (AGD7); FUNCTIONS IN: ARF GTPase activator activity, DNA binding, zinc ion binding; INVOLVED IN: regulation of ARF GTPase activity; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Arf GTPase activating protein (InterPro:IPR001164); BEST Arabidopsis thaliana protein match is: ARF-GAP domain 6 (TAIR:AT3G53710.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_181291.1
    • ARF-GAP domain 7 (AGD7); FUNCTIONS IN: ARF GTPase activator activity, DNA binding, zinc ion binding; INVOLVED IN: regulation of ARF GTPase activity; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Arf GTPase activating protein (InterPro:IPR001164); BEST Arabidopsis thaliana protein match is: ARF-GAP domain 6 (TAIR:AT3G53710.2); Has 3753 Blast hits to 3670 proteins in 253 species: Archae - 0; Bacteria - 30; Metazoa - 1888; Fungi - 664; Plants - 561; Viruses - 0; Other Eukaryotes - 610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      15755078..15757601 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129310.3 → NP_181291.1  ARF-GAP domain 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181291.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80925
      UniProtKB/TrEMBL
      A0A178VYR1, A0A5S9X4U5, A0A7G2EH59
      Conserved Domains (2) summary
      COG5347
      Location:5 → 258
      COG5347; GTPase-activating protein that regulates ARFs (ADP-ribosylation factors), involved in ARF-mediated vesicular transport [Intracellular trafficking and secretion]
      cd08830
      Location:3 → 117
      ArfGap_ArfGap1; Arf1 GTPase-activating protein 1

    2. NM_001036426.1 → NP_001031503.1  ARF-GAP domain 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031503.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80925
      UniProtKB/TrEMBL
      A0A178VYR1, A0A5S9X4U5, A0A7G2EH59
      Conserved Domains (2) summary
      COG5347
      Location:5 → 258
      COG5347; GTPase-activating protein that regulates ARFs (ADP-ribosylation factors), involved in ARF-mediated vesicular transport [Intracellular trafficking and secretion]
      cd08830
      Location:3 → 117
      ArfGap_ArfGap1; Arf1 GTPase-activating protein 1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O80925.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools