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    Disease resistance protein (TIR-NBS-LRR class) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843615, updated on 18-Sep-2024

    Summary

    Official Full Name
    Disease resistance protein (TIR-NBS-LRR class)
    Primary source
    TAIR:AT1G72840
    Locus tag
    AT1G72840
    See related
    Araport:AT1G72840
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F3N23.4; F3N23_4
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    Genomic context

    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (27409196..27413851, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Mitochondrial substrate carrier family protein Neighboring gene nuclear factor Y, subunit A3 Neighboring gene Disease resistance protein (TIR-NBS class) Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family

    General gene information

    NM_001334555.1
    NM_105942.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of plant-type hypersensitive response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    Disease resistance protein (TIR-NBS-LRR class)
    NP_001185386.1
    • Disease resistance protein (TIR-NBS-LRR class); FUNCTIONS IN: transmembrane receptor activity, ATP binding; INVOLVED IN: signal transduction, defense response, apoptosis, innate immune response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: ovule, embryo, sperm cell, root, seed; EXPRESSED DURING: E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: NB-ARC (InterPro:IPR002182), Disease resistance protein (InterPro:IPR000767), Toll-Interleukin receptor (InterPro:IPR000157); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT5G48770.1).
    NP_177427.2
    • Disease resistance protein (TIR-NBS-LRR class); FUNCTIONS IN: transmembrane receptor activity, ATP binding; INVOLVED IN: signal transduction, defense response, apoptosis, innate immune response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: ovule, embryo, sperm cell, root, seed; EXPRESSED DURING: E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: NB-ARC (InterPro:IPR002182), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT4G09430.1); Has 23413 Blast hits to 17312 proteins in 691 species: Archae - 12; Bacteria - 1355; Metazoa - 2695; Fungi - 176; Plants - 18489; Viruses - 0; Other Eukaryotes - 686 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27409196..27413851 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001198457.2NP_001185386.1  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185386.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W8L1, F4IEZ7
      Conserved Domains (3) summary
      PLN03210
      Location:15947
      PLN03210; Resistant to P. syringae 6; Provisional
      sd00033
      Location:796818
      LRR_RI; leucine-rich repeat [structural motif]
      pfam01582
      Location:15179
      TIR; TIR domain
    2. NM_001334554.1NP_001322025.1  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W8L1, F4IEZ7
    3. NM_105942.5NP_177427.2  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177427.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W8L1, Q0WQ93
      Conserved Domains (3) summary
      PLN03210
      Location:15947
      PLN03210; Resistant to P. syringae 6; Provisional
      sd00033
      Location:796818
      LRR_RI; leucine-rich repeat [structural motif]
      pfam01582
      Location:15179
      TIR; TIR domain
    4. NM_001334555.1NP_001322024.1  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W8L1, A0A1P8ASP5