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    Cytochrome C oxidase copper chaperone (COX17) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841736, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Cytochrome C oxidase copper chaperone (COX17)
    Primary source
    TAIR:AT1G53030
    Locus tag
    AT1G53030
    See related
    Araport:AT1G53030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F8L10.24; F8L10_24
    Summary
    encodes a copper chaperone, can functional complements the yeast COX17 null mutant. May play a role in the delivery of copper to mitochondria. Expressed in roots and thus may also play a role in copper transport in the roots.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (19760001..19761496, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Ubiquitin-conjugating enzyme family protein Neighboring gene Ubiquitin-conjugating enzyme family protein Neighboring gene uncharacterized protein Neighboring gene tRNA (met) cytidine acetyltransferase, putative (DUF616)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plant copper chaperones. Wintz H, et al. Biochem Soc Trans, 2002 Aug. PMID 12196180
    2. A user-friendly platform for yeast two-hybrid library screening using next generation sequencing. Erffelinck ML, et al. PLoS One, 2018. PMID 30576311, Free PMC Article
    3. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_104181.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables copper chaperone activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables copper chaperone activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables copper ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    Cytochrome C oxidase copper chaperone (COX17)
    NP_175711.1
    • Cytochrome C oxidase copper chaperone (COX17); FUNCTIONS IN: copper chaperone activity; INVOLVED IN: copper ion transport; LOCATED IN: mitochondrial intermembrane space; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome c oxidase copper chaperone (InterPro:IPR007745); BEST Arabidopsis thaliana protein match is: cytochrome c oxidase 17 (TAIR:AT3G15352.1); Has 264 Blast hits to 264 proteins in 116 species: Archae - 0; Bacteria - 0; Metazoa - 137; Fungi - 23; Plants - 55; Viruses - 0; Other Eukaryotes - 49 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      19760001..19761496 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104181.5 → NP_175711.1  Cytochrome C oxidase copper chaperone (COX17) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175711.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q2HIR2, Q8LFR7, Q94FT1
      UniProtKB/TrEMBL
      A0A178W7R4, A0A5S9WLU5
      Conserved Domains (1) summary
      pfam05051
      Location:27 → 72
      COX17; Cytochrome C oxidase copper chaperone (COX17)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94FT1.1

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