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    ATMPK8 Protein kinase superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838394, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATMPK8
    Official Full Name
    Protein kinase superfamily protein
    Primary source
    TAIR:AT1G18150
    Locus tag
    AT1G18150
    See related
    Araport:AT1G18150
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MPK8; T10F20.15
    Summary
    Encodes mitogen-activated protein kinase 8 (MPK8). MPK8 connects protein phosphorylation, Ca2+, and ROS in the wound-signaling pathway.
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    Genomic context

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    See ATMPK8 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Sequence:
    Chromosome: 1; NC_003070.9 (6244298..6247830, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Class II aaRS and biotin synthetases superfamily protein Neighboring gene laccase 1 Neighboring gene Protein kinase superfamily protein Neighboring gene FKBP-like peptidyl-prolyl cis-trans isomerase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The MPK8-TCP14 pathway promotes seed germination in Arabidopsis. Zhang W, et al. Plant J, 2019 Nov. PMID 31325184
    2. Calmodulin-dependent activation of MAP kinase for ROS homeostasis in Arabidopsis. Takahashi F, et al. Mol Cell, 2011 Mar 18. PMID 21419340
    3. Mapping out the roles of MAP kinases in plant defense. Innes RW. Trends Plant Sci, 2001 Sep. PMID 11544109
    4. Mitogen-activated protein kinase cascades in plants: a new nomenclature. MAPK Group. Trends Plant Sci, 2002 Jul. PMID 12119167
    5. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001198098.1
    NM_101675.4
    NM_179354.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables MAP kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables calmodulin binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to hydrogen peroxide IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to jasmonic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to reactive oxygen species IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to wounding IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within signal transduction IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Protein kinase superfamily protein
    NP_001185027.1
    • ATMPK8; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), MAP kinase, conserved site (InterPro:IPR003527), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: MAP kinase 15 (TAIR:AT1G73670.1).
    NP_173253.1
    • ATMPK8; FUNCTIONS IN: MAP kinase activity; INVOLVED IN: signal transduction; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), MAP kinase, conserved site (InterPro:IPR003527), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: MAP kinase 15 (TAIR:AT1G73670.1); Has 120729 Blast hits to 119418 proteins in 3824 species: Archae - 100; Bacteria - 13765; Metazoa - 44723; Fungi - 12383; Plants - 29341; Viruses - 570; Other Eukaryotes - 19847 (source: NCBI BLink).
    NP_849685.1
    • ATMPK8; FUNCTIONS IN: MAP kinase activity; INVOLVED IN: signal transduction; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), MAP kinase, conserved site (InterPro:IPR003527), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: MAP kinase 15 (TAIR:AT1G73670.1); Has 120859 Blast hits to 119547 proteins in 3851 species: Archae - 100; Bacteria - 13809; Metazoa - 44780; Fungi - 12408; Plants - 29345; Viruses - 570; Other Eukaryotes - 19847 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6244298..6247830 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001198098.1 → NP_001185027.1  Protein kinase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185027.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LM33, Q9LMS2, Q9MB23
      UniProtKB/TrEMBL
      A0A178WKE1, A0A5S9UZU8, A0A654ECU1
      Conserved Domains (1) summary
      cd07859
      Location:103 → 440
      STKc_TDY_MAPK; Catalytic domain of the Serine/Threonine Kinases, Plant TDY Mitogen-Activated Protein Kinases

    2. NM_101675.4 → NP_173253.1  Protein kinase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173253.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LM33, Q9LMS2, Q9MB23
      UniProtKB/TrEMBL
      A0A178WKE1, A0A5S9UZU8, A0A654ECU1
      Conserved Domains (1) summary
      cd07859
      Location:103 → 440
      STKc_TDY_MAPK; Catalytic domain of the Serine/Threonine Kinases, Plant TDY Mitogen-Activated Protein Kinases

    3. NM_179354.3 → NP_849685.1  Protein kinase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849685.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LM33, Q9LMS2, Q9MB23
      UniProtKB/TrEMBL
      A0A178WKE1, A0A5S9UZU8, A0A654ECU1
      Conserved Domains (1) summary
      cd07859
      Location:103 → 440
      STKc_TDY_MAPK; Catalytic domain of the Serine/Threonine Kinases, Plant TDY Mitogen-Activated Protein Kinases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LM33.2

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