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    RR18 response regulator 18 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835920, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RR18
    Official Full Name
    response regulator 18
    Primary source
    TAIR:AT5G58080
    Locus tag
    AT5G58080
    See related
    Araport:AT5G58080
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARR18; K21L19.7; K21L19_7; response regulator 18
    Summary
    member of Response Regulator: B- Type
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    Genomic context

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    See RR18 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (23501605..23504169, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene FIP1[V]-like protein Neighboring gene SHV3-like 4 Neighboring gene SNARE-like superfamily protein Neighboring gene temperature-induced lipocalin Neighboring gene O-Glycosyl hydrolases family 17 protein Neighboring gene uncharacterized protein Neighboring gene chaperone binding / ATPase activator

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis B-type response regulator 18 homomerizes and positively regulates cytokinin responses. Veerabagu M, et al. Plant J, 2012 Dec. PMID 22775331
    2. Deletion of the initial 45 residues of ARR18 induces cytokinin response in Arabidopsis. Liang Y, et al. J Genet Genomics, 2012 Jan. PMID 22293116
    3. The interaction of the Arabidopsis response regulator ARR18 with bZIP63 mediates the regulation of PROLINE DEHYDROGENASE expression. Veerabagu M, et al. Mol Plant, 2014 Oct. PMID 24948556
    4. Two-component signal transduction pathways in Arabidopsis. Hwang I, et al. Plant Physiol, 2002 Jun. PMID 12068096, Free PMC Article
    5. A PXY-Mediated Transcriptional Network Integrates Signaling Mechanisms to Control Vascular Development in Arabidopsis. Smit ME, et al. Plant Cell, 2020 Feb. PMID 31806676, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ARR18 interaction negatively interferes with the transcriptional activity of bZIP63 on the PDH1 promoter.
      Title: The interaction of the Arabidopsis response regulator ARR18 with bZIP63 mediates the regulation of PROLINE DEHYDROGENASE expression.
    2. ARR18 acts as a transcriptional regulator in plant cells, forms homodimers and positively regulates cytokinin responses.
      Title: The Arabidopsis B-type response regulator 18 homomerizes and positively regulates cytokinin responses.
    3. the initial 45 residues are critical for the inhibitory role of the receiver domain to the effector domain in ARR18
      Title: Deletion of the initial 45 residues of ARR18 induces cytokinin response in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_125193.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables phosphorelay response regulator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cytokinin-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cytokinin-activated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    response regulator 18
    NP_200616.4
    • response regulator 18 (RR18); CONTAINS InterPro DOMAIN/s: Response regulator, plant B-type (InterPro:IPR017053), Myb-like DNA-binding domain, SHAQKYF class (InterPro:IPR006447), CheY-like (InterPro:IPR011006), Myb, DNA-binding (InterPro:IPR014778), Homeodomain-like (InterPro:IPR009057), Signal transduction response regulator, receiver domain (InterPro:IPR001789), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: response regulator 12 (TAIR:AT2G25180.1); Has 83273 Blast hits to 82938 proteins in 2948 species: Archae - 359; Bacteria - 74242; Metazoa - 38; Fungi - 293; Plants - 2583; Viruses - 2; Other Eukaryotes - 5756 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      23501605..23504169 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125193.4 → NP_200616.4  response regulator 18 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4KDI4, Q9FGT7
      UniProtKB/TrEMBL
      A0A178UCV2, A0A5S9YF39
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FGT7.2

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