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    Nucleotide-sugar transporter family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836624, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Nucleotide-sugar transporter family protein
    Primary source
    TAIR:AT5G65000
    Locus tag
    AT5G65000
    See related
    Araport:AT5G65000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MXK3.23; MXK3_23
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    7
    Sequence:
    Chromosome: 5; NC_003076.8 (25964929..25967449, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene transcription factor Neighboring gene RAB GTPase homolog H1A Neighboring gene Polynucleotidyl transferase, ribonuclease H-like superfamily protein Neighboring gene asparagine synthetase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Loss of THIN EXINE2 disrupts multiple processes in the mechanism of pollen exine formation. Wang R, et al. Plant Physiol, 2021 Sep 4. PMID 34618131, Free PMC Article
    2. Arabidopsis ROCK1 transports UDP-GlcNAc/UDP-GalNAc and regulates ER protein quality control and cytokinin activity. Niemann MC, et al. Proc Natl Acad Sci U S A, 2015 Jan 6. PMID 25535363, Free PMC Article
    3. Plant-specific small peptide AtZSP1 interacts with ROCK1 to regulate organ size in Arabidopsis. Zeng Y, et al. New Phytol, 2022 Jun. PMID 35285523
    4. A large-scale genetic screen in Arabidopsis to identify genes involved in pollen exine production. Dobritsa AA, et al. Plant Physiol, 2011 Oct. PMID 21849515, Free PMC Article
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Loss of THIN EXINE2 disrupts multiple processes in the mechanism of pollen exine formation.
      Title: Loss of THIN EXINE2 disrupts multiple processes in the mechanism of pollen exine formation.
    2. ROCK1 activity is an important part of the endoplasmic reticulum quality control system, which determines the fate of aberrant proteins in the secretory pathway.[ROCK1]
      Title: Arabidopsis ROCK1 transports UDP-GlcNAc/UDP-GalNAc and regulates ER protein quality control and cytokinin activity.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_125899.4
    NM_203266.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables UDP-N-acetylgalactosamine transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sialic acid transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within UDP-N-acetylgalactosamine transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within UDP-N-acetylglucosamine transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of ERAD pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen exine formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of shoot apical meristem development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sialic acid transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Nucleotide-sugar transporter family protein
    NP_569004.1
    • Nucleotide-sugar transporter family protein; FUNCTIONS IN: nucleotide-sugar transmembrane transporter activity, sugar:hydrogen symporter activity; INVOLVED IN: carbohydrate transport, nucleotide-sugar transport; LOCATED IN: integral to membrane, Golgi membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Nucleotide-sugar transporter (InterPro:IPR007271), UDP/CMP-sugar transporter (InterPro:IPR021189); BEST Arabidopsis thaliana protein match is: Nucleotide-sugar transporter family protein (TAIR:AT4G35335.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_974995.1
    • Nucleotide-sugar transporter family protein; FUNCTIONS IN: nucleotide-sugar transmembrane transporter activity, sugar:hydrogen symporter activity; INVOLVED IN: carbohydrate transport, nucleotide-sugar transport; LOCATED IN: integral to membrane, Golgi membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Nucleotide-sugar transporter (InterPro:IPR007271); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25964929..25967449 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125899.4 → NP_569004.1  Nucleotide-sugar transporter family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_569004.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0JQ95, Q8LES0, Q8VYH1, Q9LV78
      UniProtKB/TrEMBL
      A0A178UN84, A0A5S9YH66, A0A654GE75
      Conserved Domains (1) summary
      pfam04142
      Location:46 → 312
      Nuc_sug_transp; Nucleotide-sugar transporter

    2. NM_203266.2 → NP_974995.1  Nucleotide-sugar transporter family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974995.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LES0
      Conserved Domains (1) summary
      pfam04142
      Location:46 → 242
      Nuc_sug_transp; Nucleotide-sugar transporter
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LES0.1

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