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    MAC5B CCCH-type zinc fingerfamily protein with RNA-binding domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817507, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MAC5B
    Official Full Name
    CCCH-type zinc fingerfamily protein with RNA-binding domain-containing protein
    Primary source
    TAIR:AT2G29580
    Locus tag
    AT2G29580
    See related
    Araport:AT2G29580
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F16P2.4; F16P2_4; MOS4-associated complex subunit 5B
    Summary
    Encodes MAC5B, homologous to MAC5A. MAC5A is a component of the MOS4-associated complex (MAC) that contributes to snc1- mediated autoimmunity. Homologues include AT1G07360 (MAC5A), AT2G29580 (MAC5B) and AT5G07060 (MAC5C).
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    Genomic context

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    See MAC5B in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (12651826..12654336)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene RNApolymerase 14 kDa subunit Neighboring gene tubulin beta-7 chain Neighboring gene cytosolic enolase Neighboring gene proliferating cell nuclear antigen 2 Neighboring gene Thioesterase superfamily protein Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene Plant protein 1589 of unknown function

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article
    2. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article
    3. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_128511.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    CCCH-type zinc fingerfamily protein with RNA-binding domain-containing protein
    NP_180518.1
    • CCCH-type zinc fingerfamily protein with RNA-binding domain; FUNCTIONS IN: RNA binding, zinc ion binding, nucleotide binding, nucleic acid binding; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: C globular stage, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: Zinc finger, CCCH-type (InterPro:IPR000571), RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: CCCH-type zinc fingerfamily protein with RNA-binding domain (TAIR:AT1G07360.1); Has 12789 Blast hits to 10406 proteins in 530 species: Archae - 8; Bacteria - 415; Metazoa - 5528; Fungi - 2943; Plants - 2628; Viruses - 129; Other Eukaryotes - 1138 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      12651826..12654336
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128511.2 → NP_180518.1  CCCH-type zinc fingerfamily protein with RNA-binding domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180518.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZW36
      UniProtKB/TrEMBL
      A0A178VXY2, A0A5S9X2B5
      Conserved Domains (3) summary
      TIGR01628
      Location:230 → 470
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      smart00356
      Location:157 → 181
      ZnF_C3H1; zinc finger
      cd12224
      Location:227 → 300
      RRM_RBM22; RNA recognition motif (RRM) found in Pre-mRNA-splicing factor RBM22 and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZW36.1

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