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    HAM1 GRAS family transcription factor [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819124, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HAM1
    Official Full Name
    GRAS family transcription factor
    Primary source
    TAIR:AT2G45160
    Locus tag
    AT2G45160
    See related
    Araport:AT2G45160
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA HAIRY MERISTEM 1; ATHAM1; HAIRY MERISTEM 1; LOM1; LOST MERISTEMS 1; SCARECROW-LIKE 27; SCL27; T14P1.3
    Summary
    Belongs to one of the LOM (LOST MERISTEMS) genes: AT2G45160 (LOM1), AT3G60630 (LOM2) and AT4G00150 (LOM3). LOM1 and LOM2 promote cell differentiation at the periphery of shoot meristems and help to maintain their polar organization.
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    Genomic context

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    See HAM1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (18617862..18620451, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene plant VAP homolog 12 Neighboring gene cytidinediphosphate diacylglycerol synthase 4 Neighboring gene AUTOPHAGY 8E Neighboring gene Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. miRNAs control HAM1 functions at the single-cell-layer level and are essential for normal embryogenesis in Arabidopsis. Takanashi H, et al. Plant Mol Biol, 2018 Apr. PMID 29574557
    2. LOST MERISTEMS genes regulate cell differentiation of central zone descendants in Arabidopsis shoot meristems. Schulze S, et al. Plant J, 2010 Nov. PMID 21070418
    3. Arabidopsis homologs of the petunia hairy meristem gene are required for maintenance of shoot and root indeterminacy. Engstrom EM, et al. Plant Physiol, 2011 Feb. PMID 21173022, Free PMC Article
    4. Arabidopsis miR171-targeted scarecrow-like proteins bind to GT cis-elements and mediate gibberellin-regulated chlorophyll biosynthesis under light conditions. Ma Z, et al. PLoS Genet, 2014 Aug. PMID 25101599, Free PMC Article
    5. Control of plant stem cell function by conserved interacting transcriptional regulators. Zhou Y, et al. Nature, 2015 Jan 15. PMID 25363783, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Results indicate that the control of HAIRY MERISTEM 1 (HAM1) functions at the single-cell-layer level by miR171a is essential for proper organ formation.
      Title: miRNAs control HAM1 functions at the single-cell-layer level and are essential for normal embryogenesis in Arabidopsis.
    2. AtHAM1, AtHAM2, and AtHAM3 are expressed in apical meristems and in differentiating and mature tissues of both shoot and root.
      Title: Arabidopsis homologs of the petunia hairy meristem gene are required for maintenance of shoot and root indeterminacy.
    3. findings show that LOM1(AT2G45160) and LOM2 (AT3G60630) promote cell differentiation at the periphery of shoot meristems and help to maintain their polar organization
      Title: LOST MERISTEMS genes regulate cell differentiation of central zone descendants in Arabidopsis shoot meristems.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_130079.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cell division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within root hair cell tip growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    GRAS family transcription factor
    NP_182041.1
    • HAIRY MERISTEM 1 (HAM1); CONTAINS InterPro DOMAIN/s: Transcription factor GRAS (InterPro:IPR005202); BEST Arabidopsis thaliana protein match is: GRAS family transcription factor (TAIR:AT3G60630.1); Has 2292 Blast hits to 2267 proteins in 299 species: Archae - 0; Bacteria - 2; Metazoa - 4; Fungi - 0; Plants - 2284; Viruses - 0; Other Eukaryotes - 2 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18617862..18620451 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130079.3 → NP_182041.1  GRAS family transcription factor [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_182041.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7XJM8, Q84WB1
      UniProtKB/TrEMBL
      A0A178VMD3, A0A384KUR0, B7ZWR8
      Conserved Domains (1) summary
      pfam03514
      Location:268 → 639
      GRAS; GRAS domain family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7XJM8.1

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