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    PIN1AT peptidylprolyl cis/trans isomerase, NIMA-interacting 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816316, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PIN1AT
    Official Full Name
    peptidylprolyl cis/trans isomerase, NIMA-interacting 1
    Primary source
    TAIR:AT2G18040
    Locus tag
    AT2G18040
    See related
    Araport:AT2G18040
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ''peptidylprolyl cis/trans isomerase; NIMA-interacting 1; NIMA-interacting 1''; peptidylprolyl cis/trans isomerase; PROLYL CIS/TRANS ISOMERASE; T27K22.9; T27K22_9
    Summary
    phosphorylation-specific peptidyl prolyl cis/trans isomerase (PPIase) with specificity for phosphoserine-proline bonds
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    Genomic context

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    See PIN1AT in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (7841940..7843942)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Peptide methionine sulfoxide reductase family protein Neighboring gene miscRNA Neighboring gene histone H1-3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pin1At regulates PIN1 polar localization and root gravitropism. Xi W, et al. Nat Commun, 2016 Jan 21. PMID 26791759, Free PMC Article
    2. Functional conservation of phosphorylation-specific prolyl isomerases in plants. Yao JL, et al. J Biol Chem, 2001 Apr 27. PMID 11118438
    3. Pin1At encoding a peptidyl-prolyl cis/trans isomerase regulates flowering time in Arabidopsis. Wang Y, et al. Mol Cell, 2010 Jan 15. PMID 20129060
    4. Arabidopsis plasmodesmal proteome. Fernandez-Calvino L, et al. PLoS One, 2011 Apr 20. PMID 21533090, Free PMC Article
    5. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Pin1At regulates PIN1 polar localization and root gravitropism.
      Title: Pin1At regulates PIN1 polar localization and root gravitropism.
    2. Pin1At regulates flowering, which is genetically mediated by AGL24 and SOC1.
      Title: Pin1At encoding a peptidyl-prolyl cis/trans isomerase regulates flowering time in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_127360.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables peptidyl-prolyl cis-trans isomerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables peptidyl-prolyl cis-trans isomerase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within gravitropism IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of cell cycle TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of flower development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of protein localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    peptidylprolyl cis/trans isomerase, NIMA-interacting 1
    NP_179395.1
    • ''peptidylprolyl cis/trans isomerase, NIMA-interacting 1'' (PIN1AT); FUNCTIONS IN: peptidyl-prolyl cis-trans isomerase activity; INVOLVED IN: regulation of cell cycle; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidyl-prolyl cis-trans isomerase, PpiC-type (InterPro:IPR000297); BEST Arabidopsis thaliana protein match is: FKBP-like peptidyl-prolyl cis-trans isomerase family protein (TAIR:AT1G26550.1); Has 6394 Blast hits to 6305 proteins in 1691 species: Archae - 14; Bacteria - 4880; Metazoa - 261; Fungi - 147; Plants - 126; Viruses - 0; Other Eukaryotes - 966 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      7841940..7843942
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127360.4 → NP_179395.1  peptidylprolyl cis/trans isomerase, NIMA-interacting 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179395.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q42334, Q9SL42
      UniProtKB/TrEMBL
      A0A5S9WYW6, A0A654ETT3
      Conserved Domains (1) summary
      cl29122
      Location:5 → 119
      Rotamase_2; PPIC-type PPIASE domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SL42.1

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