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    PAB3 poly(A) binding protein 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838882, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PAB3
    Official Full Name
    poly(A) binding protein 3
    Primary source
    TAIR:AT1G22760
    Locus tag
    AT1G22760
    See related
    Araport:AT1G22760
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    poly(A) binding protein 3; POLY(A) BINDING PROTEIN 3; T22J18.7; T22J18_7
    Summary
    Putative poly(A) binding protein May there fore function in posttranscriptional regulation, including mRNA turnover and translational initiation. Expression detected only in floral organs.
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    Genomic context

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    See PAB3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Sequence:
    Chromosome: 1; NC_003070.9 (8055325..8059060)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene MA3 domain-containing protein Neighboring gene RAB GTPase homolog G3B Neighboring gene uncharacterized protein Neighboring gene gigantea protein (GI) Neighboring gene Ribosomal protein S13/S18 family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of an essential requirement for the poly(A) binding protein function using cross-species complementation. Chekanova JA, et al. Curr Biol, 2001 Aug 7. PMID 11516954
    2. Evidence that poly(A) binding protein has an evolutionarily conserved function in facilitating mRNA biogenesis and export. Chekanova JA, et al. RNA, 2003 Dec. PMID 14624004, Free PMC Article
    3. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_102123.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables translation initiation factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA processing IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of nuclear-transcribed mRNA poly(A) tail shortening IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    poly(A) binding protein 3
    NP_173690.1
    • poly(A) binding protein 3 (PAB3); CONTAINS InterPro DOMAIN/s: Polyadenylate-binding protein/Hyperplastic disc protein (InterPro:IPR002004), RNA recognition motif, RNP-1 (InterPro:IPR000504), Polyadenylate binding protein, human types 1, 2, 3, 4 (InterPro:IPR006515), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: poly(A)-binding protein 5 (TAIR:AT1G71770.2); Has 52215 Blast hits to 23458 proteins in 902 species: Archae - 22; Bacteria - 3112; Metazoa - 26727; Fungi - 6853; Plants - 9433; Viruses - 0; Other Eukaryotes - 6068 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      8055325..8059060
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102123.4 → NP_173690.1  poly(A) binding protein 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173690.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O64380, O80546, Q9FYS4
      UniProtKB/TrEMBL
      A0A178W641, A0A5S9VKS4, A0A654ED08
      Conserved Domains (1) summary
      TIGR01628
      Location:49 → 644
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O64380.1

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