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    2-aminoethanethiol dioxygenase, putative (DUF1637) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818867, updated on 18-Sep-2024

    Summary

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    Official Full Name
    2-aminoethanethiol dioxygenase, putative (DUF1637)
    Primary source
    TAIR:AT2G42670
    Locus tag
    AT2G42670
    See related
    Araport:AT2G42670
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F14N22.6; F14N22_6; PCO4; plant cysteine oxidase 4
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (17771697..17774647, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Homeodomain-like superfamily protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene multiprotein bridging factor 1A Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structures of Arabidopsis thaliana oxygen-sensing plant cysteine oxidases 4 and 5 enable targeted manipulation of their activity. White MD, et al. Proc Natl Acad Sci U S A, 2020 Sep 15. PMID 32868422, Free PMC Article
    2. The plant cysteine oxidases from Arabidopsis thaliana are kinetically tailored to act as oxygen sensors. White MD, et al. J Biol Chem, 2018 Jul 27. PMID 29848548, Free PMC Article
    3. Plant cysteine oxidases are dioxygenases that directly enable arginyl transferase-catalysed arginylation of N-end rule targets. White MD, et al. Nat Commun, 2017 Mar 23. PMID 28332493, Free PMC Article
    4. Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana. Chen Z, et al. J Struct Biol, 2021 Mar. PMID 33207269
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001084573.2
    NM_001336991.1
    NM_129828.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cysteine dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to hypoxia IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in detection of hypoxia IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in peptidyl-cysteine oxidation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    2-aminoethanethiol dioxygenase, putative (DUF1637)
    NP_001078042.1
    • Protein of unknown function (DUF1637); FUNCTIONS IN: cysteamine dioxygenase activity; INVOLVED IN: oxidation reduction; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1637 (InterPro:IPR012864); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF1637) (TAIR:AT3G58670.3); Has 366 Blast hits to 366 proteins in 96 species: Archae - 0; Bacteria - 0; Metazoa - 106; Fungi - 0; Plants - 223; Viruses - 0; Other Eukaryotes - 37 (source: NCBI BLink).
    NP_565980.1
    • Protein of unknown function (DUF1637); FUNCTIONS IN: cysteamine dioxygenase activity; INVOLVED IN: oxidation reduction; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1637 (InterPro:IPR012864); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF1637) (TAIR:AT3G58670.3); Has 364 Blast hits to 364 proteins in 96 species: Archae - 0; Bacteria - 0; Metazoa - 106; Fungi - 0; Plants - 223; Viruses - 0; Other Eukaryotes - 35 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      17771697..17774647 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001084573.2 → NP_001078042.1  2-aminoethanethiol dioxygenase, putative (DUF1637) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078042.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VN46, A0A7G2EDA3
      Conserved Domains (1) summary
      pfam07847
      Location:33 → 240
      PCO_ADO

    2. NM_001336991.1 → NP_001325302.1  2-aminoethanethiol dioxygenase, putative (DUF1637) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B2S7
      Conserved Domains (1) summary
      pfam07847
      Location:16 → 172
      PCO_ADO

    3. NM_129828.3 → NP_565980.1  2-aminoethanethiol dioxygenase, putative (DUF1637) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565980.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WUD4, Q9SJI9
      UniProtKB/TrEMBL
      A0A178VQ63, A0A7G2EGE8, Q8LFV9
      Conserved Domains (1) summary
      pfam07847
      Location:33 → 239
      DUF1637; Protein of unknown function (DUF1637)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SJI9.2

    Gene LinkOut

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