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    CUL2 cullin 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839415, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CUL2
    Official Full Name
    cullin 2
    Primary source
    TAIR:AT1G02980
    Locus tag
    AT1G02980
    See related
    Araport:AT1G02980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCUL2; cullin 2; F22D16.2; F22D16_2
    Summary
    encodes an Arabidopsis cullin
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    Genomic context

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    See CUL2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    15
    Sequence:
    Chromosome: 1; NC_003070.9 (677360..681378)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene WEE1-like kinase Neighboring gene uncharacterized protein Neighboring gene peroxin 6 Neighboring gene Phototropic-responsive NPH3 family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis. Risseeuw EP, et al. Plant J, 2003 Jun. PMID 12795696
    2. Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis. Froehlich JE, et al. J Proteome Res, 2003 Jul-Aug. PMID 12938931
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001331372.1
    NM_100179.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin protein ligase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in chloroplast envelope HDA PubMed 

    General protein information

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    Preferred Names
    cullin 2
    NP_001318910.1
    • cullin 2 (CUL2); FUNCTIONS IN: ubiquitin protein ligase binding; INVOLVED IN: cell cycle, ubiquitin-dependent protein catabolic process; LOCATED IN: SCF ubiquitin ligase complex, chloroplast envelope; EXPRESSED IN: sperm cell, flower; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Cullin homology (InterPro:IPR016158), Cullin protein, neddylation domain (InterPro:IPR019559), Cullin, N-terminal (InterPro:IPR001373), Cullin repeat-like-containing domain (InterPro:IPR016159); BEST Arabidopsis thaliana protein match is: Cullin family protein (TAIR:AT1G43140.1); Has 2240 Blast hits to 2201 proteins in 240 species: Archae - 0; Bacteria - 18; Metazoa - 947; Fungi - 508; Plants - 372; Viruses - 0; Other Eukaryotes - 395 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      677360..681378
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001331372.1 → NP_001318910.1  cullin 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GY26, Q9SRZ0
      UniProtKB/TrEMBL
      A0A178W3E2, A0A5S9SAT6, A0A654E6M7
      Conserved Domains (2) summary
      smart00884
      Location:669 → 736
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:12 → 645
      Cullin; Cullin family

    2. NM_100179.4 → NP_171797.2  cullin 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_171797.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GY26, Q9SRZ0
      UniProtKB/TrEMBL
      A0A178W3E2, A0A5S9SAT6, A0A654E6M7
      Conserved Domains (2) summary
      smart00884
      Location:669 → 736
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:12 → 645
      Cullin; Cullin family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SRZ0.1

    Gene LinkOut

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