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    WOX11 WUSCHEL related homeobox 11 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821196, updated on 18-Sep-2024

    Summary

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    Official Symbol
    WOX11
    Official Full Name
    WUSCHEL related homeobox 11
    Primary source
    TAIR:AT3G03660
    Locus tag
    AT3G03660
    See related
    Araport:AT3G03660
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T12J13.6; T12J13_6; WUSCHEL related homeobox 11
    Summary
    Encodes a WUSCHEL-related homeobox gene family member with 65 amino acids in its homeodomain. Proteins in this family contain a sequence of eight residues (TLPLFPMH) downstream of the homeodomain called the WUS box.
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    Genomic context

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    See WOX11 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (889166..892229, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene cysteine synthase 26 Neighboring gene beta glucosidase 25 Neighboring gene Exostosin family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Peroxidase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Non-canonical WOX11-mediated root branching contributes to plasticity in Arabidopsis root system architecture. Sheng L, et al. Development, 2017 Sep 1. PMID 28743799, Free PMC Article
    2. Time-course transcriptome analysis reveals regulation of Arabidopsis seed dormancy by the transcription factors WOX11/12. Liao J, et al. J Exp Bot, 2023 Feb 5. PMID 36402548
    3. Transcription factors PRE3 and WOX11 are involved in the formation of new lateral roots from secondary growth taproot in A. thaliana. Baesso B, et al. Plant Biol (Stuttg), 2018 May. PMID 29450949
    4. The WOX11-LBD16 Pathway Promotes Pluripotency Acquisition in Callus Cells During De Novo Shoot Regeneration in Tissue Culture. Liu J, et al. Plant Cell Physiol, 2018 Apr 1. PMID 29361138
    5. WOX11 and 12 are involved in the first-step cell fate transition during de novo root organogenesis in Arabidopsis. Liu J, et al. Plant Cell, 2014 Mar. PMID 24642937, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Time-course transcriptome analysis reveals regulation of Arabidopsis seed dormancy by the transcription factors WOX11/12.
      Title: Time-course transcriptome analysis reveals regulation of Arabidopsis seed dormancy by the transcription factors WOX11/12.
    2. the WOX11-LBD16 pathway promotes pluripotency acquisition in callus cells.
      Title: The WOX11-LBD16 Pathway Promotes Pluripotency Acquisition in Callus Cells During De Novo Shoot Regeneration in Tissue Culture.
    3. involved in the formation of new lateral roots from secondary growth taproot
      Title: Transcription factors PRE3 and WOX11 are involved in the formation of new lateral roots from secondary growth taproot in A. thaliana.
    4. The discovery of WOX11-mediated root-derived roots reveals a previously uncharacterized pathway that confers plasticity during the generation of root system architecture in response to different inductive cues.
      Title: Non-canonical WOX11-mediated root branching contributes to plasticity in Arabidopsis root system architecture.
    5. the expression switch from WOX11/12 to WOX5/7 is critical for initiation of the root primordium during de novo root organogenesis.
      Title: Transcription Factors WOX11/12 Directly Activate WOX5/7 to Promote Root Primordia Initiation and Organogenesis.
    6. WOX11 directly responds to a wounding-induced auxin maximum in and surrounding the procambium and acts redundantly with its homolog WOX12 to upregulate LATERAL ORGAN BOUNDARIES DOMAIN16 (LBD16) and LBD29
      Title: WOX11 and 12 are involved in the first-step cell fate transition during de novo root organogenesis in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_001125091.2
    NM_001337479.1
    NM_111237.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adventitious root development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within adventitious root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within auxin-activated signaling pathway IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    WUSCHEL related homeobox 11
    NP_001118563.1
    • WUSCHEL related homeobox 11 (WOX11); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent; LOCATED IN: chloroplast; CONTAINS InterPro DOMAIN/s: Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057); BEST Arabidopsis thaliana protein match is: WUSCHEL related homeobox 12 (TAIR:AT5G17810.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_187016.2
    • WUSCHEL related homeobox 11 (WOX11); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent; LOCATED IN: chloroplast; CONTAINS InterPro DOMAIN/s: Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057); BEST Arabidopsis thaliana protein match is: WUSCHEL related homeobox 12 (TAIR:AT5G17810.2); Has 592 Blast hits to 582 proteins in 72 species: Archae - 0; Bacteria - 0; Metazoa - 52; Fungi - 5; Plants - 532; Viruses - 0; Other Eukaryotes - 3 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      889166..892229 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001337480.1 → NP_001326145.1  WUSCHEL related homeobox 11 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V783, A0A1I9LND7

    2. NM_001125091.2 → NP_001118563.1  WUSCHEL related homeobox 11 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001118563.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V783, A0A5S9X9D9, B3H5D3
      Conserved Domains (1) summary
      cl00084
      Location:32 → 84
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

    3. NM_001337479.1 → NP_001326146.1  WUSCHEL related homeobox 11 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V783, A0A1I9LND8

    4. NM_111237.3 → NP_187016.2  WUSCHEL related homeobox 11 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187016.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6X7J3, Q9SS66
      UniProtKB/TrEMBL
      A0A178V783
      Conserved Domains (1) summary
      pfam00046
      Location:32 → 84
      Homeobox; Homeobox domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6X7J3.2

    Gene LinkOut

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