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    RIC6 ROP-interactive CRIB motif-containing protein 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816562, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RIC6
    Official Full Name
    ROP-interactive CRIB motif-containing protein 6
    Primary source
    TAIR:AT2G20430
    Locus tag
    AT2G20430
    See related
    Araport:AT2G20430
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ROP-interactive CRIB motif-containing protein 6; T13C7.2
    Summary
    encodes a member of a novel protein family that contains contain a CRIB (for Cdc42/Rac-interactive binding) motif required for their specific interaction with GTP-bound Rop1 (plant-specific Rho GTPase). Most similar to RIC7 and RIC8 (subfamily group II). Gene is expressed predominantly in inflorescence and flower tissue.
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    Genomic context

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    See RIC6 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (8808414..8810200, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene ATP citrate lyase (ACL) family protein Neighboring gene ncRNA Neighboring gene Ypt/Rab-GAP domain of gyp1p superfamily protein Neighboring gene Ribosomal protein L14

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A genome-wide analysis of Arabidopsis Rop-interactive CRIB motif-containing proteins that act as Rop GTPase targets. Wu G, et al. Plant Cell, 2001 Dec. PMID 11752391, Free PMC Article
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_127602.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within pollen tube growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ROP-interactive CRIB motif-containing protein 6
    NP_179633.2
    • ROP-interactive CRIB motif-containing protein 6 (RIC6); CONTAINS InterPro DOMAIN/s: PAK-box/P21-Rho-binding (InterPro:IPR000095); BEST Arabidopsis thaliana protein match is: PAK-box/P21-Rho-binding family protein (TAIR:AT4G28556.1); Has 458 Blast hits to 374 proteins in 75 species: Archae - 0; Bacteria - 0; Metazoa - 116; Fungi - 30; Plants - 184; Viruses - 3; Other Eukaryotes - 125 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      8808414..8810200 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127602.4 → NP_179633.2  ROP-interactive CRIB motif-containing protein 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179633.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0MEN4, Q1PF35, Q9SIM6
      UniProtKB/TrEMBL
      A0A178W0R0, A0A5S9WZM7, A0A654EUJ5
      Conserved Domains (1) summary
      cd00132
      Location:32 → 68
      CRIB; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1PF35.1

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