ATK1 kinesin 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ATK1
Official Full Name: kinesin 1
Primary source: TAIR:AT4G21270
Locus tag: AT4G21270
See related: Araport:AT4G21270
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F7J7.210; F7J7_210; KATA; KATAP; kinesin 1; KINESIN-LIKE PROTEIN IN ARABIDOPSIS THALIANA A; KINESIN-LIKE PROTEIN IN ARABIDOPSIS THALIANA A PROTEIN; KINESIN-LIKE PROTEIN IN ARABIDOPSIS THALIANA A; KINESIN-LIKE PROTEIN IN ARABIDOPSIS THALIANA A PROTEIN
Summary: Encodes a kinesin-like motor protein heavy chain. Loss of function mutations have reduced fertility and are defective in spindle formation in male meiosis.
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Genomic context

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See ATK1 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 17

Sequence:: Chromosome: 4; NC_003075.7 (11329319..11334168, complement)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Arabidopsis AtKIN14a and AtKIN14b genes encoding highly similar kinesins are two of the most closely related Arabidopsis paralogs. They together play important roles in controlling plant reproductive development. [AtKIN14a]
Title: Functional divergence of the duplicated AtKIN14a and AtKIN14b genes: critical roles in Arabidopsis meiosis and gametophyte development.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_118246.2

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables microtubule binding	IEA Inferred from Electronic Annotation more info
enables minus-end-directed microtubule motor activity	IDA Inferred from Direct Assay more info	PubMed
enables minus-end-directed microtubule motor activity	TAS Traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within anastral spindle assembly involved in male meiosis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in microtubule-based movement	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
part_of minus-end kinesin complex	TAS Traceable Author Statement more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info
located_in phragmoplast	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: kinesin 1

NP_193859.1

kinesin 1 (ATK1); CONTAINS InterPro DOMAIN/s: Kinesin, motor region, conserved site (InterPro:IPR019821), Kinesin, motor domain (InterPro:IPR001752); BEST Arabidopsis thaliana protein match is: kinesin 5 (TAIR:AT4G05190.1); Has 113981 Blast hits to 63024 proteins in 3025 species: Archae - 1256; Bacteria - 16796; Metazoa - 54341; Fungi - 9779; Plants - 6646; Viruses - 430; Other Eukaryotes - 24733 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

11329319..11334168 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_118246.2 → NP_193859.1 kinesin 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_193859.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q07970, Q7FKK6

UniProtKB/TrEMBL

A0A178UZL2, A0A5S9XUF7

Conserved Domains (2) summary

COG1196
Location:116 → 433

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd01366
Location:429 → 774

KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins