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    Calcium-dependent lipid-binding (CaLB domain) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 833752, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Calcium-dependent lipid-binding (CaLB domain) family protein
    Primary source
    TAIR:AT5G37740
    Locus tag
    AT5G37740
    See related
    Araport:AT5G37740
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    K12B20.22; K12B20_22
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (14991880..14993781)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene miscRNA Neighboring gene Chaperone DnaJ-domain superfamily protein Neighboring gene Chaperone DnaJ-domain superfamily protein Neighboring gene EF hand calcium-binding protein family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Calcium-dependent oligomerization of CAR proteins at cell membrane modulates ABA signaling. Diaz M, et al. Proc Natl Acad Sci U S A, 2016 Jan 19. PMID 26719420, Free PMC Article
    2. Recruitment of HAB1 and SnRK2.2 by C2-domain protein CAR1 in plasma membrane ABA signaling. Guo AY, et al. Plant J, 2024 Jul. PMID 38597817
    3. CAR modulates plasma membrane nano-organization and immune signaling downstream of RALF1-FERONIA signaling pathway. Chen W, et al. New Phytol, 2023 Mar. PMID 36527240
    4. C2-domain abscisic acid-related proteins mediate the interaction of PYR/PYL/RCAR abscisic acid receptors with the plasma membrane and regulate abscisic acid sensitivity in Arabidopsis. Rodriguez L, et al. Plant Cell, 2014 Dec. PMID 25465408, Free PMC Article
    5. Toward an interaction map of the two-component signaling pathway of Arabidopsis thaliana. Dortay H, et al. J Proteome Res, 2008 Sep. PMID 18642946

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001203502.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTPase activator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables lipid binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables phospholipid binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein homodimerization activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of abscisic acid-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to abscisic acid IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Calcium-dependent lipid-binding (CaLB domain) family protein
    NP_001190431.1
    • Calcium-dependent lipid-binding (CaLB domain) family protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: Calcium-dependent lipid-binding (CaLB domain) family protein (TAIR:AT1G66360.1).
    NP_198590.1
    • Calcium-dependent lipid-binding (CaLB domain) family protein; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: Calcium-dependent lipid-binding (CaLB domain) family protein (TAIR:AT1G66360.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      14991880..14993781
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123133.4 → NP_198590.1  Calcium-dependent lipid-binding (CaLB domain) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198590.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0Z2Y5, Q9FHP6
      UniProtKB/TrEMBL
      A0A178UGX2, A0A5S9Y9E1
      Conserved Domains (1) summary
      cd04038
      Location:5 → 151
      C2_ArfGAP; C2 domain present in Arf GTPase Activating Proteins (GAP)

    2. NM_001203502.1 → NP_001190431.1  Calcium-dependent lipid-binding (CaLB domain) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190431.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4K8L6
      Conserved Domains (1) summary
      cl14603
      Location:5 → 161
      C2; C2 domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FHP6.1

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