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    GEX2 gamete expressed 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834974, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GEX2
    Official Full Name
    gamete expressed 2
    Primary source
    TAIR:AT5G49150
    Locus tag
    AT5G49150
    See related
    Araport:AT5G49150
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATGEX2; gamete expressed 2; K21P3.2; K21P3_2
    Summary
    Encodes a transmembrane domain containing protein expressed in sperm cells. Target promoter of the male germline-specific transcription factor DUO1.
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    Genomic context

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    See GEX2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    17
    Sequence:
    Chromosome: 5; NC_003076.8 (19924354..19929256)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene MATE efflux family protein Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family Neighboring gene ncRNA Neighboring gene methyltransferase 1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gamete attachment requires GEX2 for successful fertilization in Arabidopsis. Mori T, et al. Curr Biol, 2014 Jan 20. PMID 24388850
    2. Green sperm. Identification of male gamete promoters in Arabidopsis. Engel ML, et al. Plant Physiol, 2005 Aug. PMID 16055690, Free PMC Article
    3. The R2R3 MYB transcription factor DUO1 activates a male germline-specific regulon essential for sperm cell differentiation in Arabidopsis. Borg M, et al. Plant Cell, 2011 Feb. PMID 21285328, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Ka/Ks analyses indicate relatively rapid evolution of GEX2, like other proteins involved in male and female interactions
      Title: Gamete attachment requires GEX2 for successful fertilization in Arabidopsis.
    2. The expression of GEX2 during pollen development is reported.
      Title: Green sperm. Identification of male gamete promoters in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001344819.1
    NM_001344820.1
    NM_001344821.1
    NM_001344822.1
    NM_124292.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within fusion of sperm to egg plasma membrane involved in double fertilization forming a zygote and endosperm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen sperm cell differentiation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    gamete expressed 2
    NP_199726.3
    • gamete expressed 2 (GEX2); CONTAINS InterPro DOMAIN/s: Filamin/ABP280 repeat (InterPro:IPR001298), Immunoglobulin-like fold (InterPro:IPR013783), Immunoglobulin E-set (InterPro:IPR014756), Filamin/ABP280 repeat-like (InterPro:IPR017868); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      19924354..19929256
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001344816.1 → NP_001330856.1  gamete expressed 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9YCW9, W0TY53

    2. NM_001344817.1 → NP_001330859.1  gamete expressed 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UJS1, A0A1P8BC34

    3. NM_001344818.1 → NP_001330860.1  gamete expressed 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UJS1, A0A1P8BC47

    4. NM_124292.3 → NP_199726.3  gamete expressed 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199726.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4K4R6, Q49L64, Q9FJ23
      UniProtKB/TrEMBL
      A0A178UJS1
      Conserved Domains (1) summary
      pfam00630
      Location:427 → 481
      Filamin; Filamin/ABP280 repeat

    5. NM_001344819.1 → NP_001330858.1  gamete expressed 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BC31, A0A5S9YCW9

    6. NM_001344820.1 → NP_001330862.1  gamete expressed 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UJS1, A0A1P8BC40

    7. NM_001344821.1 → NP_001330861.1  gamete expressed 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BC45

    8. NM_001344822.1 → NP_001330857.1  gamete expressed 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BC26
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4K4R6.1

    Gene LinkOut

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