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    Cleavage/polyadenylation specificity factor, 25kDa subunit [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828660, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Cleavage/polyadenylation specificity factor, 25kDa subunit
    Primary source
    TAIR:AT4G25550
    Locus tag
    AT4G25550
    See related
    Araport:AT4G25550
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    M7J2.80; M7J2_80
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    7
    Sequence:
    Chromosome: 4; NC_003075.7 (13048367..13051273)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene SEUSS-like 1 Neighboring gene FLOWERING WAGENINGEN Neighboring gene homolog of DNA mismatch repair protein MSH3 Neighboring gene myb domain protein 18 Neighboring gene Cytochrome b561/ferric reductase transmembrane protein family Neighboring gene CAP160 protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An Arabidopsis Fip1 homolog interacts with RNA and provides conceptual links with a number of other polyadenylation factor subunits. Forbes KP, et al. J Biol Chem, 2006 Jan 6. PMID 16282318
    2. Plant-specific ribosome biogenesis factors in Arabidopsis thaliana with essential function in rRNA processing. Palm D, et al. Nucleic Acids Res, 2019 Feb 28. PMID 30576513, Free PMC Article
    3. Arabidopsis mRNA polyadenylation machinery: comprehensive analysis of protein-protein interactions and gene expression profiling. Hunt AG, et al. BMC Genomics, 2008 May 14. PMID 18479511, Free PMC Article
    4. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Van Leene J, et al. Mol Syst Biol, 2010 Aug 10. PMID 20706207, Free PMC Article
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_118687.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA 3'-end processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within rRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of mRNA cleavage factor complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Cleavage/polyadenylation specificity factor, 25kDa subunit
    NP_194285.2
    • Cleavage/polyadenylation specificity factor, 25kDa subunit; CONTAINS InterPro DOMAIN/s: Cleavage/polyadenylation specificity factor, 25kDa subunit (InterPro:IPR016706); BEST Arabidopsis thaliana protein match is: homolog of CFIM-25 (TAIR:AT4G29820.1); Has 397 Blast hits to 397 proteins in 170 species: Archae - 0; Bacteria - 0; Metazoa - 171; Fungi - 88; Plants - 70; Viruses - 0; Other Eukaryotes - 68 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      13048367..13051273
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118687.3 → NP_194285.2  Cleavage/polyadenylation specificity factor, 25kDa subunit [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194285.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65606, Q570Y1, Q8GXS3, Q9M0K5
      UniProtKB/TrEMBL
      A0A178V0E0, A0A5S9XW50, A0A7G2F7C3
      Conserved Domains (1) summary
      pfam13869
      Location:5 → 193
      NUDIX_2; Nucleotide hydrolase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8GXS3.1

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