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    RPN12a regulatory particle non-ATPase 12A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842760, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RPN12a
    Official Full Name
    regulatory particle non-ATPase 12A
    Primary source
    TAIR:AT1G64520
    Locus tag
    AT1G64520
    See related
    Araport:AT1G64520
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F1N19.9; F1N19_9; regulatory particle non-ATPase 12A
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    Genomic context

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    See RPN12a in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (23956269..23958461)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene DEK, chromatin associated protein Neighboring gene Glutaredoxin family protein Neighboring gene Translation elongation factor EF1B/ribosomal protein S6 family protein Neighboring gene Plant regulator RWP-RK family protein Neighboring gene miscRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cytokinin growth responses in Arabidopsis involve the 26S proteasome subunit RPN12. Smalle J, et al. Plant Cell, 2002 Jan. PMID 11826296, Free PMC Article
    2. Arabidopsis PUB22 and PUB23 are homologous U-Box E3 ubiquitin ligases that play combinatory roles in response to drought stress. Cho SK, et al. Plant Cell, 2008 Jul. PMID 18664614, Free PMC Article
    3. 26S proteasome regulatory particle mutants have increased oxidative stress tolerance. Kurepa J, et al. Plant J, 2008 Jan. PMID 17971041
    4. Arabidopsis eIF3e interacts with subunits of the ribosome, Cop9 signalosome and proteasome. Paz-Aviram T, et al. Plant Signal Behav, 2008 Jun. PMID 19704582, Free PMC Article
    5. A tandem affinity purification-based technology platform to study the cell cycle interactome in Arabidopsis thaliana. Van Leene J, et al. Mol Cell Proteomics, 2007 Jul. PMID 17426018

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    NM_105127.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cotyledon development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within flower development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within post-embryonic root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within proteasome assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within proteasome-mediated ubiquitin-dependent protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of anthocyanin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to auxin IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cytokinin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cytokinin IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to heat IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to misfolded protein IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within skotomorphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast envelope HDA PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus TAS
    Traceable Author Statement
    more info
    		 PubMed 
    part_of proteasome complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of proteasome regulatory particle IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    regulatory particle non-ATPase 12A
    NP_176633.1
    • regulatory particle non-ATPase 12A (RPN12a); FUNCTIONS IN: peptidase activity; INVOLVED IN: in 14 processes; LOCATED IN: proteasome complex, nucleus, proteasome regulatory particle, lid subcomplex, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: 26S proteasome non-ATPase regulatory subunit Rpn12 (InterPro:IPR006746), SAC3/GANP/Nin1/mts3/eIF-3 p25 (InterPro:IPR005062); BEST Arabidopsis thaliana protein match is: regulatory particle non-ATPase 12B (TAIR:AT5G42040.1); Has 474 Blast hits to 474 proteins in 207 species: Archae - 0; Bacteria - 0; Metazoa - 195; Fungi - 129; Plants - 70; Viruses - 0; Other Eukaryotes - 80 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      23956269..23958461
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105127.4 → NP_176633.1  regulatory particle non-ATPase 12A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176633.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6XJF4, Q9SGW3
      UniProtKB/TrEMBL
      A0A178WH62, A0A5S9WS04
      Conserved Domains (1) summary
      cl24019
      Location:118 → 221
      CSN8_PSD8_EIF3K; CSN8/PSMD8/EIF3K family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SGW3.1

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