SRS2 P-loop containing nucleoside triphosphate hydrolases superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: SRS2
Official Full Name: P-loop containing nucleoside triphosphate hydrolases superfamily protein
Primary source: TAIR:AT4G25120
Locus tag: AT4G25120
See related: Araport:AT4G25120
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ARABIDOPSIS THALIANA SUPPRESSOR OF RAD SIX-SCREEN MUTANT 2; ATSRS2; F24A6.8; SUPPRESSOR OF RAD SIX-SCREEN MUTANT 2
Summary: Encodes a homolog of the yeast SRS2 (Suppressor of RAD Six-screen mutant 2) helicase. The Arabidopsis SRS2 is a functional 3#Aeo- to 5#Aeo-helicase. Biochemical studies show that SRS2 disrupts recombinogenic DNA intermediates and facilitates single strand annealing.
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Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

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AtSRS2 is a functional 3'- to 5'-helicase.[AtSRS2]
Title: A SRS2 homolog from Arabidopsis thaliana disrupts recombinogenic DNA intermediates and facilitates single strand annealing.

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NM_001341722.1

Function	Evidence Code	Pubs
enables 3'-5' DNA helicase activity	IDA Inferred from Direct Assay more info	PubMed
enables DNA helicase activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA duplex unwinding	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within DNA recombination	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within DNA rewinding	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	ISM Inferred from Sequence Model more info

Preferred Names: P-loop containing nucleoside triphosphate hydrolases superfamily protein

NP_001320059.1

SUPPRESSOR OF RAD SIX-SCREEN MUTANT 2 (SRS2); CONTAINS InterPro DOMAIN/s: DNA helicase, UvrD-like, C-terminal (InterPro:IPR014017), Helicase, superfamily 1, UvrD-related (InterPro:IPR014016), DNA helicase, UvrD/REP type (InterPro:IPR000212); Has 26201 Blast hits to 22116 proteins in 2711 species: Archae - 259; Bacteria - 18888; Metazoa - 18; Fungi - 176; Plants - 81; Viruses - 13; Other Eukaryotes - 6766 (source: NCBI BLink).

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The following sections contain reference sequences that belong to a specific genome build. Explain