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    LisH/CRA/RING-U-box domains-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829944, updated on 18-Sep-2024

    Summary

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    Official Full Name
    LisH/CRA/RING-U-box domains-containing protein
    Primary source
    TAIR:AT4G37880
    Locus tag
    AT4G37880
    See related
    Araport:AT4G37880
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T28I19.160; T28I19_160
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    2
    Sequence:
    Chromosome: 4; NC_003075.7 (17809637..17811659)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene SPT2 chromatin protein Neighboring gene phosphoenolpyruvate carboxykinase 1 Neighboring gene ncRNA Neighboring gene Zinc finger (C3HC4-type RING finger) family protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Interactions of an Arabidopsis RanBPM homologue with LisH-CTLH domain proteins revealed high conservation of CTLH complexes in eukaryotes. Tomaštíková E, et al. BMC Plant Biol, 2012 Jun 7. PMID 22676313, Free PMC Article
    2. A user-friendly platform for yeast two-hybrid library screening using next generation sequencing. Erffelinck ML, et al. PLoS One, 2018. PMID 30576311, Free PMC Article
    3. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_119949.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    LisH/CRA/RING-U-box domains-containing protein
    NP_195501.1
    • LisH/CRA/RING-U-box domains-containing protein; FUNCTIONS IN: zinc ion binding; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ran binding protein, CRA domain (InterPro:IPR019589), Zinc finger, RING-type (InterPro:IPR001841), CTLH, C-terminal LisH motif (InterPro:IPR006595), LisH dimerisation motif (InterPro:IPR006594), Ran binding protein-like, CRA domain (InterPro:IPR013144); BEST Arabidopsis thaliana protein match is: zinc ion binding (TAIR:AT2G22690.2); Has 833 Blast hits to 829 proteins in 195 species: Archae - 0; Bacteria - 0; Metazoa - 364; Fungi - 234; Plants - 138; Viruses - 0; Other Eukaryotes - 97 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      17809637..17811659
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119949.5 → NP_195501.1  LisH/CRA/RING-U-box domains-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195501.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9T075
      UniProtKB/TrEMBL
      A0A178UYR8, A0A5S9Y012
      Conserved Domains (2) summary
      COG5109
      Location:28 → 388
      COG5109; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
      pfam10607
      Location:150 → 292
      CLTH; CTLH/CRA C-terminal to LisH motif domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9T075.1

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