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    NPC6 non-specific phospholipase C6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824021, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NPC6
    Official Full Name
    non-specific phospholipase C6
    Primary source
    TAIR:AT3G48610
    Locus tag
    AT3G48610
    See related
    Araport:AT3G48610
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    non-specific phospholipase C6
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    Genomic context

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    See NPC6 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (18011475..18014204, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene nuclear factor Y, subunit C1 Neighboring gene SWIB complex BAF60b domain-containing protein Neighboring gene Outer membrane OMP85 family protein Neighboring gene miscRNA Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Non-specific phospholipases C2 and C6 redundantly function in pollen tube growth via triacylglycerol production in Arabidopsis. Bose D, et al. Plant J, 2021 Apr. PMID 33506578
    2. Non-specific phospholipases C, NPC2 and NPC6, are required for root growth in Arabidopsis. Ngo AH, et al. Plant J, 2019 Nov. PMID 31400172
    3. A pair of nonspecific phospholipases C, NPC2 and NPC6, are involved in gametophyte development and glycerolipid metabolism in Arabidopsis. Ngo AH, et al. New Phytol, 2018 Jul. PMID 29655284
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Non-specific phospholipases C2 and C6 redundantly function in pollen tube growth via triacylglycerol production in Arabidopsis.
      Title: Non-specific phospholipases C2 and C6 redundantly function in pollen tube growth via triacylglycerol production in Arabidopsis.
    2. NPC6 is involved in the root growth by producing phosphocholine.
      Title: Non-specific phospholipases C, NPC2 and NPC6, are required for root growth in Arabidopsis.
    3. The results demonstrate that NPC2 and NPC6 play crucial roles in gametogenesis during flower development.
      Title: A pair of nonspecific phospholipases C, NPC2 and NPC6, are involved in gametophyte development and glycerolipid metabolism in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_114720.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phospholipase C activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within gametophyte development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within phospholipid catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within root development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    non-specific phospholipase C6
    NP_190430.2
    • non-specific phospholipase C6 (NPC6); FUNCTIONS IN: hydrolase activity, acting on ester bonds; LOCATED IN: endomembrane system; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phosphoesterase (InterPro:IPR007312); BEST Arabidopsis thaliana protein match is: non-specific phospholipase C1 (TAIR:AT1G07230.1); Has 2244 Blast hits to 2129 proteins in 399 species: Archae - 32; Bacteria - 1880; Metazoa - 0; Fungi - 127; Plants - 152; Viruses - 0; Other Eukaryotes - 53 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      18011475..18014204 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114720.4 → NP_190430.2  non-specific phospholipase C6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190430.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8H965, Q9SMN8
      UniProtKB/TrEMBL
      A0A178VI01, A0A5S9XIZ4
      Conserved Domains (1) summary
      pfam04185
      Location:39 → 394
      Phosphoesterase; Phosphoesterase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8H965.1

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