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    D-isomer specific 2-hydroxyacid dehydrogenase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819171, updated on 18-Sep-2024

    Summary

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    Official Full Name
    D-isomer specific 2-hydroxyacid dehydrogenase family protein
    Primary source
    TAIR:AT2G45630
    Locus tag
    AT2G45630
    See related
    Araport:AT2G45630
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F17K2.16
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (18795926..18797263)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene Nucleotidyltransferase family protein Neighboring gene miscRNA Neighboring gene SIN3 associated polypeptide P18

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of Arabidopsis thaliana Hydroxyphenylpyruvate Reductases in the Tyrosine Conversion Pathway. Xu JJ, et al. Front Plant Sci, 2018. PMID 30233632, Free PMC Article
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_130125.1
    NM_201964.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    colocalizes_with cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    D-isomer specific 2-hydroxyacid dehydrogenase family protein
    NP_566049.1
    • D-isomer specific 2-hydroxyacid dehydrogenase family protein; FUNCTIONS IN: NAD or NADH binding, binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, catalytic activity; INVOLVED IN: metabolic process; EXPRESSED IN: stem; CONTAINS InterPro DOMAIN/s: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (InterPro:IPR006139), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: D-isomer specific 2-hydroxyacid dehydrogenase family protein (TAIR:AT1G12550.1); Has 6623 Blast hits to 6621 proteins in 1548 species: Archae - 250; Bacteria - 4438; Metazoa - 370; Fungi - 171; Plants - 170; Viruses - 0; Other Eukaryotes - 1224 (source: NCBI BLink).
    NP_973693.1
    • D-isomer specific 2-hydroxyacid dehydrogenase family protein; FUNCTIONS IN: NAD or NADH binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, binding, catalytic activity, cofactor binding; INVOLVED IN: metabolic process; EXPRESSED IN: stem; CONTAINS InterPro DOMAIN/s: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (InterPro:IPR006139), D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (InterPro:IPR006140), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: D-isomer specific 2-hydroxyacid dehydrogenase family protein (TAIR:AT1G12550.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18795926..18797263
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130125.1 → NP_566049.1  D-isomer specific 2-hydroxyacid dehydrogenase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566049.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O64643, Q945K4
      Conserved Domains (1) summary
      cl21454
      Location:22 → 166
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    2. NM_201964.2 → NP_973693.1  D-isomer specific 2-hydroxyacid dehydrogenase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973693.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9X797, A0A654FCS2, Q67XB5, Q67Y01
      Conserved Domains (1) summary
      cd12156
      Location:22 → 329
      HPPR; Hydroxy(phenyl)pyruvate Reductase, D-isomer-specific 2-hydroxyacid-related dehydrogenase
    Nucleotide Protein
    Heading Accession and Version

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