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    SETH1 phosphatidylinositolglycan synthase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818062, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SETH1
    Official Full Name
    phosphatidylinositolglycan synthase family protein
    Primary source
    TAIR:AT2G34980
    Locus tag
    AT2G34980
    See related
    Araport:AT2G34980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F19I3.21; F19I3_21
    Summary
    Encodes a putative phosphatidylinositol-glycan synthase subunit C gene. It is involved in the first step of the glycosylphosphatidylinositol (GPI) biosynthetic pathway.
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    Genomic context

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    See SETH1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (14748877..14749878)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene cationic amino acid transporter 5 Neighboring gene Trimeric LpxA-like enzyme Neighboring gene tRNA-Thr Neighboring gene RING/U-box superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SETH1 and SETH2, two components of the glycosylphosphatidylinositol anchor biosynthetic pathway, are required for pollen germination and tube growth in Arabidopsis. Lalanne E, et al. Plant Cell, 2004 Jan. PMID 14671020, Free PMC Article
    2. A user-friendly platform for yeast two-hybrid library screening using next generation sequencing. Erffelinck ML, et al. PLoS One, 2018. PMID 30576311, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_129050.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    contributes_to phosphatidylinositol N-acetylglucosaminyltransferase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in GPI anchor biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within GPI anchor biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen germination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen tube growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylinositolglycan synthase family protein
    NP_181043.1
    • SETH1; CONTAINS InterPro DOMAIN/s: Phosphatidylinositol N-acetylglucosaminyltransferase (InterPro:IPR009450); Has 335 Blast hits to 331 proteins in 171 species: Archae - 0; Bacteria - 0; Metazoa - 120; Fungi - 117; Plants - 38; Viruses - 0; Other Eukaryotes - 60 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      14748877..14749878
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129050.2 → NP_181043.1  phosphatidylinositolglycan synthase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181043.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O64761
      UniProtKB/TrEMBL
      A0A178VQ18, A0A5S9X4J5
      Conserved Domains (1) summary
      pfam06432
      Location:15 → 293
      GPI2; Phosphatidylinositol N-acetylglucosaminyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O64761.1

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