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    EDE1 ENDOSPERM DEFECTIVE protein (DUF566) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819026, updated on 18-Sep-2024

    Summary

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    Official Symbol
    EDE1
    Official Full Name
    ENDOSPERM DEFECTIVE protein (DUF566)
    Primary source
    TAIR:AT2G44190
    Locus tag
    AT2G44190
    See related
    Araport:AT2G44190
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    EMB3116; EMBRYO DEFECTIVE 3116; ENDOSPERM DEFECTIVE 1; F6E13.32; QWRF domain containing 5; QWRF5
    Summary
    Encodes a novel microtubule binding protein that preferentially associates with nuclear microtubules during mitosis and is essential during the mitotic and cytokinetic stages that generate the endosperm and embryo.
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    Genomic context

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    See EDE1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (18272119..18274679)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene Acyl-CoA N-acyltransferases (NAT) superfamily protein Neighboring gene methionine aminopeptidase 2A Neighboring gene pre-mRNA splicing factor domain-containing protein Neighboring gene uncharacterized protein Neighboring gene pre-mRNA splicing factor domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ENDOSPERM DEFECTIVE1 Is a Novel Microtubule-Associated Protein Essential for Seed Development in Arabidopsis. Pignocchi C, et al. Plant Cell, 2009 Jan. PMID 19151224, Free PMC Article
    2. The Mitotic Function of Augmin Is Dependent on Its Microtubule-Associated Protein Subunit EDE1 in Arabidopsis thaliana. Lee YJ, et al. Curr Biol, 2017 Dec 18. PMID 29225022
    3. Interaction of a 14-3-3 protein with the plant microtubule-associated protein EDE1. Pignocchi C, et al. Ann Bot, 2011 May. PMID 21558460, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. EDE1, but not AUG8, is associated with acentrosomal spindle and phragmoplast microtubule (MT) arrays in patterns indistinguishable from those of the AUG1-7 subunits and the gamma-tubulin complex proteins (GCPs) that exhibit biased localization toward MT minus ends.
      Title: The Mitotic Function of Augmin Is Dependent on Its Microtubule-Associated Protein Subunit EDE1 in Arabidopsis thaliana.
    2. 14-3-3 upsilon most strongly associates with EDE1 in its free form, but also weakly when EDE1 is bound to microtubules.
      Title: Interaction of a 14-3-3 protein with the plant microtubule-associated protein EDE1.
    3. EDE1 is a novel plant-specific microtubule-associated protein essential for microtubule function during the mitotic and cytokinetic stages that generate the Arabidopsis endosperm and embryo. [EDE1]
      Title: ENDOSPERM DEFECTIVE1 Is a Novel Microtubule-Associated Protein Essential for Seed Development in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_129982.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables microtubule binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within endosperm cellularization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within endosperm development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within microtubule cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within seed development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nuclear microtubule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ENDOSPERM DEFECTIVE protein (DUF566)
    NP_181947.1
    • ENDOSPERM DEFECTIVE 1 (EDE1); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF566 (InterPro:IPR007573); BEST Arabidopsis thaliana protein match is: Family of unknown function (DUF566) (TAIR:AT3G60000.2); Has 456 Blast hits to 444 proteins in 94 species: Archae - 0; Bacteria - 6; Metazoa - 141; Fungi - 55; Plants - 202; Viruses - 3; Other Eukaryotes - 49 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18272119..18274679
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129982.3 → NP_181947.1  ENDOSPERM DEFECTIVE protein (DUF566) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181947.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80588
      UniProtKB/TrEMBL
      A0A5S9X762, A0A654FCC4
      Conserved Domains (1) summary
      pfam04484
      Location:256 → 435
      QWRF; QWRF family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O80588.1

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