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    TIM10 Tim10/DDP family zinc finger protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817502, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TIM10
    Official Full Name
    Tim10/DDP family zinc finger protein
    Primary source
    TAIR:AT2G29530
    Locus tag
    AT2G29530
    See related
    Araport:AT2G29530
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtTIM10; F16P2.9; F16P2_9; TRANSLOCASE OF THE INNER MEMBRANE 10
    Summary
    Encodes a small zinc finger-like protein that is a component of the mitochondrial protein import apparatus. Together with AtTIM9, AtTIM10 is non-redundantly essential for maintaining mitochondrial function of early embryo proper cells and endosperm free-nuclei.
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    Genomic context

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    See TIM10 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (12640800..12642387, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene hypothetical protein (DUF3527) Neighboring gene tRNA-Val Neighboring gene Inositol phosphorylceramide synthase 3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RNApolymerase 14 kDa subunit Neighboring gene tubulin beta-7 chain Neighboring gene cytosolic enolase Neighboring gene proliferating cell nuclear antigen 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TRANSLOCASE OF THE INNER MEMBRANE9 and 10 are essential for maintaining mitochondrial function during early embryo cell and endosperm free nucleus divisions in Arabidopsis. Deng Y, et al. Plant Physiol, 2014 Oct. PMID 25104724, Free PMC Article
    2. A transcriptomic and proteomic characterization of the Arabidopsis mitochondrial protein import apparatus and its response to mitochondrial dysfunction. Lister R, et al. Plant Physiol, 2004 Feb. PMID 14730085, Free PMC Article
    3. Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis. Klopffleisch K, et al. Mol Syst Biol, 2011 Sep 27. PMID 21952135, Free PMC Article
    4. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    5. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001084507.2
    NM_001161068.1
    NM_128506.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within mitochondrion organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrial intermembrane space HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in peroxisome HDA PubMed 

    General protein information

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    Preferred Names
    Tim10/DDP family zinc finger protein
    NP_001077976.1
    • TIM10; FUNCTIONS IN: P-P-bond-hydrolysis-driven protein transmembrane transporter activity; INVOLVED IN: protein import into mitochondrial inner membrane, protein targeting to mitochondrion; LOCATED IN: mitochondrion, mitochondrial inner membrane, mitochondrial intermembrane space; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Mitochondrial inner membrane translocase complex, Tim8/9/10/13-zinc finger-like (InterPro:IPR004217); Has 468 Blast hits to 468 proteins in 187 species: Archae - 0; Bacteria - 0; Metazoa - 159; Fungi - 177; Plants - 83; Viruses - 0; Other Eukaryotes - 49 (source: NCBI BLink).
    NP_001154540.1
    • TIM10; FUNCTIONS IN: P-P-bond-hydrolysis-driven protein transmembrane transporter activity; INVOLVED IN: protein targeting to mitochondrion, protein import into mitochondrial inner membrane; LOCATED IN: mitochondrion, mitochondrial inner membrane, mitochondrial intermembrane space; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Mitochondrial inner membrane translocase complex, Tim8/9/10/13-zinc finger-like (InterPro:IPR004217); Has 390 Blast hits to 390 proteins in 171 species: Archae - 0; Bacteria - 0; Metazoa - 139; Fungi - 145; Plants - 65; Viruses - 0; Other Eukaryotes - 41 (source: NCBI BLink).
    NP_565682.1
    • TIM10; FUNCTIONS IN: P-P-bond-hydrolysis-driven protein transmembrane transporter activity; INVOLVED IN: protein import into mitochondrial inner membrane, protein targeting to mitochondrion; LOCATED IN: mitochondrion, mitochondrial inner membrane, mitochondrial intermembrane space; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Mitochondrial inner membrane translocase complex, Tim8/9/10/13-zinc finger-like (InterPro:IPR004217); Has 468 Blast hits to 468 proteins in 187 species: Archae - 0; Bacteria - 0; Metazoa - 159; Fungi - 177; Plants - 83; Viruses - 0; Other Eukaryotes - 49 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      12640800..12642387 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001084507.2 → NP_001077976.1  Tim10/DDP family zinc finger protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077976.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZW33
      UniProtKB/TrEMBL
      A0A178VVN0, A0A384L021, Q0WRM1
      Conserved Domains (1) summary
      pfam02953
      Location:15 → 74
      zf-Tim10_DDP; Tim10/DDP family zinc finger

    2. NM_128506.3 → NP_565682.1  Tim10/DDP family zinc finger protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565682.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZW33
      UniProtKB/TrEMBL
      A0A178VVN0, A0A384L021, Q0WRM1
      Conserved Domains (1) summary
      pfam02953
      Location:15 → 74
      zf-Tim10_DDP; Tim10/DDP family zinc finger

    3. NM_001161068.1 → NP_001154540.1  Tim10/DDP family zinc finger protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001154540.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4IKQ3
      Conserved Domains (1) summary
      pfam02953
      Location:15 → 98
      zf-Tim10_DDP; Tim10/DDP family zinc finger
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZW33.1

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