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    RFO1 Wall-associated kinase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844306, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RFO1
    Official Full Name
    Wall-associated kinase family protein
    Primary source
    TAIR:AT1G79670
    Locus tag
    AT1G79670
    See related
    Araport:AT1G79670
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F20B17.27; F20B17_27; RESISTANCE TO FUSARIUM OXYSPORUM 1; WAKL22
    Summary
    Encodes a receptor-like kinase that does not contain an extracellular leucine-rich repeat domain. A novel type of dominant disease-resistance protein that confers resistance to a broad spectrum of Fusarium races.
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    Genomic context

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    See RFO1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (29976725..29979356, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Rad23 UV excision repair protein family Neighboring gene ephrin-A3 protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene WALL ASSOCIATED KINASE (WAK)-LIKE 10 Neighboring gene nudix hydrolase homolog 3 Neighboring gene Integrase-type DNA-binding superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The WAK-like protein RFO1 acts as a sensor of the pectin methylation status in Arabidopsis cell walls to modulate root growth and defense. Huerta AI, et al. Mol Plant, 2023 May 1. PMID 37002606, Free PMC Article
    2. Visualizing and quantifying Fusarium oxysporum in the plant host. Diener A. Mol Plant Microbe Interact, 2012 Dec. PMID 22894177
    3. RESISTANCE TO FUSARIUM OXYSPORUM 1, a dominant Arabidopsis disease-resistance gene, is not race specific. Diener AC, et al. Genetics, 2005 Sep. PMID 15965251, Free PMC Article
    4. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_106616.5
    NM_179577.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Wall-associated kinase family protein
    NP_178085.1
    • RESISTANCE TO FUSARIUM OXYSPORUM 1 (RFO1); FUNCTIONS IN: kinase activity; INVOLVED IN: response to fungus; LOCATED IN: endomembrane system, integral to membrane, cell wall; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Wall-associated kinase (InterPro:IPR013695), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: wall associated kinase-like 2 (TAIR:AT1G16130.1); Has 120817 Blast hits to 119164 proteins in 4285 species: Archae - 142; Bacteria - 13548; Metazoa - 44699; Fungi - 10352; Plants - 33861; Viruses - 488; Other Eukaryotes - 17727 (source: NCBI BLink).
    NP_849908.1
    • RESISTANCE TO FUSARIUM OXYSPORUM 1 (RFO1); FUNCTIONS IN: kinase activity; INVOLVED IN: response to fungus; LOCATED IN: endomembrane system, integral to membrane, cell wall; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Wall-associated kinase (InterPro:IPR013695), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: wall associated kinase-like 2 (TAIR:AT1G16130.1); Has 120550 Blast hits to 118930 proteins in 4262 species: Archae - 142; Bacteria - 13516; Metazoa - 44650; Fungi - 10334; Plants - 33695; Viruses - 488; Other Eukaryotes - 17725 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      29976725..29979356 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106616.5 → NP_178085.1  Wall-associated kinase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178085.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4JQ55, Q8RY17, Q9MA08
      UniProtKB/TrEMBL
      A0A178WG77, A0A5S9WVU3
      Conserved Domains (2) summary
      pfam08488
      Location:174 → 279
      WAK; Wall-associated kinase
      cd14066
      Location:427 → 694
      STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs

    2. NM_179577.1 → NP_849908.1  Wall-associated kinase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849908.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9WVU3, F4IF87
      Conserved Domains (4) summary
      smart00221
      Location:386 → 650
      STYKc; Protein kinase; unclassified specificity
      pfam08488
      Location:146 → 242
      WAK; Wall-associated kinase
      cd14066
      Location:390 → 657
      STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
      pfam13947
      Location:34 → 146
      GUB_WAK_bind; Wall-associated receptor kinase galacturonan-binding
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8RY17.1

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