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    SMO2-1 sterol 4-alpha-methyl-oxidase 2-1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837254, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SMO2-1
    Official Full Name
    sterol 4-alpha-methyl-oxidase 2-1
    Primary source
    TAIR:AT1G07420
    Locus tag
    AT1G07420
    See related
    Araport:AT1G07420
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Arabidopsis thaliana sterol 4-alpha-methyl oxidase 1; ATSMO1; ATSMO2; F22G5.23; F22G5_23; STEROL 4-ALPHA-METHYL-OXIDASE 2; sterol 4-alpha-methyl-oxidase 2-1
    Summary
    Arabidopsis thaliana sterol 4-alpha-methyl-oxidase mRNA
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    Genomic context

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    See SMO2-1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Sequence:
    Chromosome: 1; NC_003070.9 (2277555..2280502)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene HSP20-like chaperones superfamily protein Neighboring gene RAB GTPase homolog A2B Neighboring gene highly ABA-induced PP2C protein 2 Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sterol Methyl Oxidases Affect Embryo Development via Auxin-Associated Mechanisms. Zhang X, et al. Plant Physiol, 2016 May. PMID 27006488, Free PMC Article
    2. The Arabidopsis SMO2, a homologue of yeast TRM112, modulates progression of cell division during organ growth. Hu Z, et al. Plant J, 2010 Feb. PMID 19929876
    3. Functional identification of sterol-4alpha-methyl oxidase cDNAs from Arabidopsis thaliana by complementation of a yeast erg25 mutant lacking sterol-4alpha-methyl oxidation. Darnet S, et al. FEBS Lett, 2001 Nov 9. PMID 11707264
    4. Plant sterol biosynthesis: identification of two distinct families of sterol 4alpha-methyl oxidases. Darnet S, et al. Biochem J, 2004 Mar 15. PMID 14653780, Free PMC Article
    5. Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis. Froehlich JE, et al. J Proteome Res, 2003 Jul-Aug. PMID 12938931

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    NM_100616.3
    NM_202048.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables C-4 methylsterol oxidase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within 4-alpha-methyl-delta7-sterol oxidation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast envelope HDA PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sterol 4-alpha-methyl-oxidase 2-1
    NP_563789.1
    • sterol 4-alpha-methyl-oxidase 2-1 (SMO2-1); FUNCTIONS IN: C-4 methylsterol oxidase activity, 4-alpha-methyl-delta7-sterol-4alpha-methyl oxidase activity; INVOLVED IN: oxidation reduction, fatty acid biosynthetic process; LOCATED IN: chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Fatty acid hydroxylase (InterPro:IPR006694); BEST Arabidopsis thaliana protein match is: sterol 4-alpha-methyl-oxidase 2-2 (TAIR:AT2G29390.2); Has 2893 Blast hits to 2888 proteins in 513 species: Archae - 0; Bacteria - 699; Metazoa - 429; Fungi - 685; Plants - 484; Viruses - 3; Other Eukaryotes - 593 (source: NCBI BLink).
    NP_973777.1
    • sterol 4-alpha-methyl-oxidase 2-1 (SMO2-1); FUNCTIONS IN: C-4 methylsterol oxidase activity, 4-alpha-methyl-delta7-sterol-4alpha-methyl oxidase activity; INVOLVED IN: oxidation reduction, fatty acid biosynthetic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Fatty acid hydroxylase (InterPro:IPR006694); BEST Arabidopsis thaliana protein match is: sterol 4-alpha-methyl-oxidase 2-2 (TAIR:AT2G29390.3); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      2277555..2280502
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100616.3 → NP_563789.1  sterol 4-alpha-methyl-oxidase 2-1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563789.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DFL5, Q8LBE1, Q8VWZ8, Q9LNW2
      UniProtKB/TrEMBL
      A0A178WAJ4, A0A5S9T3A5, A0A5S9X2F0
      Conserved Domains (1) summary
      pfam04116
      Location:112 → 247
      FA_hydroxylase; Fatty acid hydroxylase superfamily

    2. NM_202048.2 → NP_973777.1  sterol 4-alpha-methyl-oxidase 2-1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973777.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VWZ8
      Conserved Domains (2) summary
      COG3000
      Location:34 → 209
      ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]
      pfam04116
      Location:74 → 209
      FA_hydroxylase; Fatty acid hydroxylase superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VWZ8.1

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