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    CNX3 cofactor of nitrate reductase and xanthine dehydrogenase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839445, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CNX3
    Official Full Name
    cofactor of nitrate reductase and xanthine dehydrogenase 3
    Primary source
    TAIR:AT1G01290
    Locus tag
    AT1G01290
    See related
    Araport:AT1G01290
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    cofactor of nitrate reductase and xanthine dehydrogenase 3; F6F3.9; F6F3_9
    Summary
    COFACTOR OF NITRATE REDUCTASE AND XANTHINE DEHYDROGENASE 3. Encodes a protein involved in molybdenum cofactor biosynthesis. Homologous to E.coli MoaC. Expression is low in all tissues examined, except in roots. Appears to have targeting signals for chloroplast or mitochondria
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    Genomic context

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    See CNX3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (114202..116407)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene tRNA-Gln Neighboring gene cytochrome P450, family 703, subfamily A, polypeptide 2 Neighboring gene Eukaryotic aspartyl protease family protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Visualization and quantification of protein interactions in the biosynthetic pathway of molybdenum cofactor in Arabidopsis thaliana. Kaufholdt D, et al. J Exp Bot, 2013 Apr. PMID 23630326, Free PMC Article
    2. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157
    3. Isolation of two Arabidopsis cDNAs involved in early steps of molybdenum cofactor biosynthesis by functional complementation of Escherichia coli mutants. Hoff T, et al. J Biol Chem, 1995 Mar 17. PMID 7890743
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001160827.2
    NM_100011.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables catalytic activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables cyclic pyranopterin monophosphate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within Mo-molybdopterin cofactor biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cofactor of nitrate reductase and xanthine dehydrogenase 3
    NP_001154299.1
    • cofactor of nitrate reductase and xanthine dehydrogenase 3 (CNX3); CONTAINS InterPro DOMAIN/s: Molybdopterin cofactor biosynthesis C (MoaC) domain (InterPro:IPR002820); Has 5242 Blast hits to 5240 proteins in 1916 species: Archae - 213; Bacteria - 3669; Metazoa - 104; Fungi - 75; Plants - 45; Viruses - 0; Other Eukaryotes - 1136 (source: NCBI BLink).
    NP_171636.1
    • cofactor of nitrate reductase and xanthine dehydrogenase 3 (CNX3); CONTAINS InterPro DOMAIN/s: Molybdopterin cofactor biosynthesis C (MoaC) domain (InterPro:IPR002820); Has 5242 Blast hits to 5240 proteins in 1916 species: Archae - 213; Bacteria - 3669; Metazoa - 104; Fungi - 75; Plants - 45; Viruses - 0; Other Eukaryotes - 1136 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      114202..116407
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100011.4 → NP_171636.1  cofactor of nitrate reductase and xanthine dehydrogenase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_171636.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q1ECR4, Q39056
      UniProtKB/TrEMBL
      A0A178WGD5, A0A654E6A1, A0A7G2DR10
      Conserved Domains (1) summary
      PLN02375
      Location:1 → 269
      PLN02375; molybderin biosynthesis protein CNX3

    2. NM_001160827.2 → NP_001154299.1  cofactor of nitrate reductase and xanthine dehydrogenase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001154299.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q1ECR4, Q39056
      UniProtKB/TrEMBL
      A0A178WGD5, A0A654E6A1, A0A7G2DR10
      Conserved Domains (1) summary
      PLN02375
      Location:1 → 269
      PLN02375; molybderin biosynthesis protein CNX3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39056.1

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