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    ZML1 ZIM-like 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821670, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ZML1
    Official Full Name
    ZIM-like 1
    Primary source
    TAIR:AT3G21175
    Locus tag
    AT3G21175
    See related
    Araport:AT3G21175
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    GATA TRANSCRIPTION FACTOR 24; GATA24; TIFY2B; ZIM LIKE 1; ZIM-like 1
    Summary
    member of a novel family of plant-specific GATA-type transcription factors.
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    Genomic context

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    See ZML1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    8
    Sequence:
    Chromosome: 3; NC_003074.8 (7422026..7424989)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene F-box/associated interaction domain protein Neighboring gene F-box/associated interaction domain protein Neighboring gene autoinhibited Ca(2+)-ATPase 9 Neighboring gene O-fucosyltransferase family protein Neighboring gene ncRNA Neighboring gene proton gradient regulation 7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The CRYPTOCHROME1-dependent response to excess light is mediated through the transcriptional activators ZINC FINGER PROTEIN EXPRESSED IN INFLORESCENCE MERISTEM LIKE1 and ZML2 in Arabidopsis. Shaikhali J, et al. Plant Cell, 2012 Jul. PMID 22786870, Free PMC Article
    2. Telomerase Interaction Partners-Insight from Plants. Fulnečková J, et al. Int J Mol Sci, 2021 Dec 29. PMID 35008793, Free PMC Article
    3. Tandem affinity purification of AtTERT reveals putative interaction partners of plant telomerase in vivo. Majerská J, et al. Protoplasma, 2017 Jul. PMID 27853871
    4. Establishment of Expression in the SHORTROOT-SCARECROW Transcriptional Cascade through Opposing Activities of Both Activators and Repressors. Sparks EE, et al. Dev Cell, 2016 Dec 5. PMID 27923776, Free PMC Article
    5. A PXY-Mediated Transcriptional Network Integrates Signaling Mechanisms to Control Vascular Development in Arabidopsis. Smit ME, et al. Plant Cell, 2020 Feb. PMID 31806676, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The ZML2 and ZML1 GATA transcription factors are two essential components of the cry1-mediated photoprotective response.
      Title: The CRYPTOCHROME1-dependent response to excess light is mediated through the transcriptional activators ZINC FINGER PROTEIN EXPRESSED IN INFLORESCENCE MERISTEM LIKE1 and ZML2 in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001125197.2
    NM_113012.4
    NM_180287.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ZIM-like 1
    NP_001118669.1
    • ZIM-like 1 (ZML1); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Tify (InterPro:IPR010399), CCT domain (InterPro:IPR010402); BEST Arabidopsis thaliana protein match is: ZIM-LIKE 2 (TAIR:AT1G51600.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_566676.1
    • ZIM-like 1 (ZML1); FUNCTIONS IN: sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding; INVOLVED IN: regulation of transcription, DNA-dependent; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, NHR/GATA-type (InterPro:IPR013088), Tify (InterPro:IPR010399), CCT domain (InterPro:IPR010402), Zinc finger, GATA-type (InterPro:IPR000679); BEST Arabidopsis thaliana protein match is: ZIM-LIKE 2 (TAIR:AT1G51600.2); Has 2137 Blast hits to 2132 proteins in 202 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 496; Plants - 1587; Viruses - 0; Other Eukaryotes - 54 (source: NCBI BLink).
    NP_850618.1
    • ZIM-like 1 (ZML1); FUNCTIONS IN: sequence-specific DNA binding, zinc ion binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, NHR/GATA-type (InterPro:IPR013088), Tify (InterPro:IPR010399), Zinc finger, GATA-type (InterPro:IPR000679), CCT domain (InterPro:IPR010402); BEST Arabidopsis thaliana protein match is: ZIM-LIKE 2 (TAIR:AT1G51600.2); Has 2151 Blast hits to 2146 proteins in 203 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 499; Plants - 1598; Viruses - 0; Other Eukaryotes - 54 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      7422026..7424989
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180287.5 → NP_850618.1  ZIM-like 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850618.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9XE59, A0A654FA63
      Conserved Domains (4) summary
      smart00979
      Location:73 → 108
      TIFY; This short possible domain is found in a variety of plant transcription factors that contain GATA domains as well as other motifs
      smart00401
      Location:217 → 255
      ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
      cd00202
      Location:217 → 266
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
      pfam06203
      Location:141 → 184
      CCT; CCT motif

    2. NM_113012.4 → NP_566676.1  ZIM-like 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566676.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GXL7, Q8LF08, Q94B66, Q9LU42
      UniProtKB/TrEMBL
      A0A5S9XE59, A0A654FA63
      Conserved Domains (4) summary
      smart00979
      Location:73 → 108
      TIFY; This short possible domain is found in a variety of plant transcription factors that contain GATA domains as well as other motifs
      smart00401
      Location:219 → 257
      ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
      cd00202
      Location:219 → 268
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
      pfam06203
      Location:143 → 186
      CCT; CCT motif

    3. NM_001125197.2 → NP_001118669.1  ZIM-like 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001118669.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3H4L8
      Conserved Domains (2) summary
      smart00979
      Location:73 → 108
      TIFY; This short possible domain is found in a variety of plant transcription factors that contain GATA domains as well as other motifs
      pfam06203
      Location:141 → 184
      CCT; CCT motif
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8GXL7.2

    Gene LinkOut

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