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    EGY3 ethylene-dependent gravitropism-deficient and yellow-green-like 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838366, updated on 18-Sep-2024

    Summary

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    Official Symbol
    EGY3
    Official Full Name
    ethylene-dependent gravitropism-deficient and yellow-green-like 3
    Primary source
    TAIR:AT1G17870
    Locus tag
    AT1G17870
    See related
    Araport:AT1G17870
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATEGY3; ETHYLENE-DEPENDENT GRAVITROPISM-DEFICIENT AND YELLOW-GREEN-LIKE 3; F2H15.10; F2H15_10
    Summary
    S2P-like putative metalloprotease, also contain transmembrane helices near their C-termini and many of them, five of seven, contain a conserved zinc-binding motif HEXXH. Homolog of EGY1. Each of the EGY1 and EGY-like proteins share two additional highly conserved motifs, the previously reported NPDG motif (aa 442#Aei454 in EGY1, Rudner et al., 1999) and a newly defined GNLR motif (aa 171#Aei179 in EGY1). The GNLR motif is a novel signature motif unique to EGY1 and EGY-like proteins as well as other EGY1 orthologs found in cyanobacteria.
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    Genomic context

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    See EGY3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (6149939..6152222, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene white-brown complex-like protein Neighboring gene Rhodanese/Cell cycle control phosphatase superfamily protein Neighboring gene ncRNA Neighboring gene Kunitz family trypsin and protease inhibitor protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene basic transcription factor 3 Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EGY3 mediates chloroplastic ROS homeostasis and promotes retrograde signaling in response to salt stress in Arabidopsis. Zhuang Y, et al. Cell Rep, 2021 Jul 13. PMID 34260941
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. EGY3 mediates chloroplastic ROS homeostasis and promotes retrograde signaling in response to salt stress in Arabidopsis.
      Title: EGY3 mediates chloroplastic ROS homeostasis and promotes retrograde signaling in response to salt stress in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_101650.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in response to salt stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ethylene-dependent gravitropism-deficient and yellow-green-like 3
    NP_173229.1
    • ETHYLENE-DEPENDENT GRAVITROPISM-DEFICIENT AND YELLOW-GREEN-LIKE 3 (EGY3); INVOLVED IN: response to high light intensity, response to hydrogen peroxide, response to heat; LOCATED IN: chloroplast; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 9 growth stages; BEST Arabidopsis thaliana protein match is: Peptidase M50 family protein (TAIR:AT5G35220.1); Has 660 Blast hits to 652 proteins in 203 species: Archae - 107; Bacteria - 240; Metazoa - 53; Fungi - 13; Plants - 117; Viruses - 1; Other Eukaryotes - 129 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6149939..6152222 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101650.3 → NP_173229.1  ethylene-dependent gravitropism-deficient and yellow-green-like 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173229.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WWS5, Q9LMU1
      UniProtKB/TrEMBL
      A0A654EAN3
      Conserved Domains (1) summary
      cl10020
      Location:276 → 489
      S2P-M50; Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LMU1.1

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