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    PLDGAMMA2 phospholipase D gamma 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 826789, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PLDGAMMA2
    Official Full Name
    phospholipase D gamma 2
    Primary source
    TAIR:AT4G11830
    Locus tag
    AT4G11830
    See related
    Araport:AT4G11830
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AT4G11835; phospholipase D gamma 2; T26M18.40; T26M18_40
    Summary
    Encodes one of three phospholipase D enzymes of the gamma class.
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    Genomic context

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    See PLDGAMMA2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    12
    Sequence:
    Chromosome: 4; NC_003075.7 (7115681..7121919, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Major Facilitator Superfamily with SPX (SYG1/Pho81/XPR1) domain-containing protein Neighboring gene hydroxymethylglutaryl-CoA synthase / HMG-CoA synthase / 3-hydroxy-3-methylglutaryl coenzyme A synthase Neighboring gene phospholipase D gamma 3 Neighboring gene Interleukin-1 receptor-associated kinase 4 protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Suppression of phospholipase Dγs confers increased aluminum resistance in Arabidopsis thaliana. Zhao J, et al. PLoS One, 2011. PMID 22163277, Free PMC Article
    2. High heterogeneity within the ribosomal proteins of the Arabidopsis thaliana 80S ribosome. Giavalisco P, et al. Plant Mol Biol, 2005 Mar. PMID 15821981
    3. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001340736.1
    NM_001340737.1
    NM_117252.6
    NM_179208.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables N-acylphosphatidylethanolamine-specific phospholipase D activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phospholipase D activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phospholipase D activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within membrane lipid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in phosphatidylcholine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phospholipid catabolic process TAS
    Traceable Author Statement
    more info
    		  
    acts_upstream_of_or_within response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosolic ribosome HDA PubMed 

    General protein information

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    Preferred Names
    phospholipase D gamma 2
    NP_192920.3
    • phospholipase D gamma 2 (PLDGAMMA2); FUNCTIONS IN: phospholipase D activity; INVOLVED IN: phospholipid catabolic process; LOCATED IN: cytosolic ribosome, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), Phospholipase D (InterPro:IPR015679), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), Phospholipase D, plant (InterPro:IPR011402), Phospholipase D/Transphosphatidylase (InterPro:IPR001736), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: phospholipase D gamma 3 (TAIR:AT4G11840.1); Has 2065 Blast hits to 1596 proteins in 399 species: Archae - 2; Bacteria - 528; Metazoa - 398; Fungi - 435; Plants - 545; Viruses - 0; Other Eukaryotes - 157 (source: NCBI BLink).
    NP_849539.1
    • phospholipase D gamma 2 (PLDGAMMA2); FUNCTIONS IN: phospholipase D activity; INVOLVED IN: phospholipid catabolic process; LOCATED IN: cytosolic ribosome, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), Phospholipase D (InterPro:IPR015679), Phospholipase D, plant (InterPro:IPR011402), Phospholipase D/Transphosphatidylase (InterPro:IPR001736), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: phospholipase D gamma 3 (TAIR:AT4G11840.1); Has 2194 Blast hits to 1721 proteins in 407 species: Archae - 2; Bacteria - 532; Metazoa - 481; Fungi - 448; Plants - 557; Viruses - 0; Other Eukaryotes - 174 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      7115681..7121919 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179208.3 → NP_849539.1  phospholipase D gamma 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849539.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654FNI6
      Conserved Domains (4) summary
      PLN03008
      Location:51 → 823
      PLN03008; Phospholipase D delta
      pfam12357
      Location:747 → 815
      PLD_C; Phospholipase D C terminal
      cl14603
      Location:31 → 152
      C2; C2 domain
      cl15239
      Location:502 → 720
      PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

    2. NM_001340736.1 → NP_001328718.1  phospholipase D gamma 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B5I3

    3. NM_117252.6 → NP_192920.3  phospholipase D gamma 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192920.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3EA52, Q9T051, Q9XH77
      UniProtKB/TrEMBL
      A0A654FNI6
      Conserved Domains (4) summary
      cd04015
      Location:33 → 184
      C2_plant_PLD; C2 domain present in plant phospholipase D (PLD)
      PLN03008
      Location:31 → 855
      PLN03008; Phospholipase D delta
      pfam12357
      Location:779 → 847
      PLD_C; Phospholipase D C terminal
      cl15239
      Location:534 → 752
      PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

    4. NM_001340737.1 → NP_001328719.1  phospholipase D gamma 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B5J2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9T051.3

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