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    PP2-A1 phloem protein 2-A1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827728, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PP2-A1
    Official Full Name
    phloem protein 2-A1
    Primary source
    TAIR:AT4G19840
    Locus tag
    AT4G19840
    See related
    Araport:AT4G19840
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPP2-A1; ATPP2A-1; phloem protein 2-A1; T16H5.200; T16H5_200
    Summary
    encodes a phloem lectin, similar to phloem lectin in cucumber and celery. Gene is expressed in the phloem, predominantly in the companion cells.
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    Genomic context

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    See PP2-A1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (10773804..10775942)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Glycosyl hydrolase family protein with chitinase insertion domain-containing protein Neighboring gene Glycosyl hydrolase family protein with chitinase insertion domain-containing protein Neighboring gene FKBP-like peptidyl-prolyl cis-trans isomerase family protein Neighboring gene lectin-like protein Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene Galactose oxidase/kelch repeat superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Aphid salivary protein Mp1 facilitates infestation by binding phloem protein 2-A1 in Arabidopsis. Wang Z, et al. Biochem Biophys Res Commun, 2021 Oct 1. PMID 34364288
    2. Molecular chaperone function of Arabidopsis thaliana phloem protein 2-A1, encodes a protein similar to phloem lectin. Lee JR, et al. Biochem Biophys Res Commun, 2014 Jan 3. PMID 24269669
    3. Harpin-induced expression and transgenic overexpression of the phloem protein gene AtPP2-A1 in Arabidopsis repress phloem feeding of the green peach aphid Myzus persicae. Zhang C, et al. BMC Plant Biol, 2011 Jan 13. PMID 21226963, Free PMC Article
    4. Binding properties of the N-acetylglucosamine and high-mannose N-glycan PP2-A1 phloem lectin in Arabidopsis. Beneteau J, et al. Plant Physiol, 2010 Jul. PMID 20442276, Free PMC Article
    5. Diversity of the superfamily of phloem lectins (phloem protein 2) in angiosperms. Dinant S, et al. Plant Physiol, 2003 Jan. PMID 12529520, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Aphid salivary protein Mp1 facilitates infestation by binding phloem protein 2-A1 in Arabidopsis.
      Title: Aphid salivary protein Mp1 facilitates infestation by binding phloem protein 2-A1 in Arabidopsis.
    2. These results suggest that the AtPP2-A1 molecular chaperone protein plays a critical role in the Arabidopsis defense system against diverse external stresses including fungal pathogenic attack and heat shock.
      Title: Molecular chaperone function of Arabidopsis thaliana phloem protein 2-A1, encodes a protein similar to phloem lectin.
    3. A repression of phloem feeding was induced by HrpNEa in wild-type (WT) Arabidopsis but not in atpp2-a1/E/142, the plant mutant that had a defect in the AtPP2-A1 gene, the most HrpNEa-responsive of 30 AtPP2 genes.
      Title: Harpin-induced expression and transgenic overexpression of the phloem protein gene AtPP2-A1 in Arabidopsis repress phloem feeding of the green peach aphid Myzus persicae.
    4. These results indicate the presence in PP2-A1 of several carbohydrate-binding sites, with potentially different functions in the trafficking of endogenous proteins or in interactions with phloem-feeding insects.[PP2-A1]
      Title: Binding properties of the N-acetylglucosamine and high-mannose N-glycan PP2-A1 phloem lectin in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_118104.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables carbohydrate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables proteoglycan binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to insect IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    phloem protein 2-A1
    NP_193719.1
    • phloem protein 2-A1 (PP2-A1); BEST Arabidopsis thaliana protein match is: phloem protein 2-A4 (TAIR:AT1G33920.1); Has 488 Blast hits to 483 proteins in 39 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 488; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      10773804..10775942
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118104.5 → NP_193719.1  phloem protein 2-A1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193719.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81865, Q8LDY2
      UniProtKB/TrEMBL
      A0A5S9XU58
      Conserved Domains (1) summary
      pfam14299
      Location:93 → 244
      PP2; Phloem protein 2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O81865.1

    Gene LinkOut

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