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    CAT6 cationic amino acid transporter 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830355, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CAT6
    Official Full Name
    cationic amino acid transporter 6
    Primary source
    TAIR:AT5G04770
    Locus tag
    AT5G04770
    See related
    Araport:AT5G04770
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA CATIONIC AMINO ACID TRANSPORTER 6; ATCAT6; cationic amino acid transporter 6; MUK11.10
    Summary
    Encodes a member of the cationic amino acid transporter (CAT) subfamily of amino acid polyamine choline transporters. Does not mediate efficient uptake of basic amino acids in yeast or Xenopus systems but can transport neutral and acidic amino acid analogs. Expressed in sink tissues. Induced during infestation of roots by the plant parasitic root-knot nematode, Meloidogyne incognita. Localized in the plasma membrane.
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    Genomic context

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    See CAT6 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (1378621..1382478)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Duplicated homeodomain-like superfamily protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AtCAT6, a sink-tissue-localized transporter for essential amino acids in Arabidopsis. Hammes UZ, et al. Plant J, 2006 Nov. PMID 17052324
    2. Molecular and functional characterization of a family of amino acid transporters from Arabidopsis. Su YH, et al. Plant Physiol, 2004 Oct. PMID 15377779, Free PMC Article
    3. Uncovering Arabidopsis membrane protein interactome enriched in transporters using mating-based split ubiquitin assays and classification models. Chen J, et al. Front Plant Sci, 2012. PMID 22737156, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001342790.1
    NM_001342791.1
    NM_120559.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables amino acid transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT enables basic amino acid transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables basic amino acid transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within amino acid transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to nematode IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cationic amino acid transporter 6
    NP_196097.1
    • cationic amino acid transporter 6 (CAT6); CONTAINS InterPro DOMAIN/s: Cationic amino acid transporter (InterPro:IPR015606), Amino acid/polyamine transporter I (InterPro:IPR002293), Amino acid permease domain (InterPro:IPR004841); BEST Arabidopsis thaliana protein match is: cationic amino acid transporter 7 (TAIR:AT3G10600.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      1378621..1382478
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120559.4 → NP_196097.1  cationic amino acid transporter 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196097.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LZ20
      UniProtKB/TrEMBL
      A0A178UKC8, A0A5S9Y202
      Conserved Domains (1) summary
      TIGR00906
      Location:51 → 562
      2A0303; cationic amino acid transport permease

    2. NM_001342790.1 → NP_001330125.1  cationic amino acid transporter 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B9T8

    3. NM_001342791.1 → NP_001330124.1  cationic amino acid transporter 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B9U0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LZ20.1

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