IAMT1 IAA carboxylmethyltransferase 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: IAMT1
Official Full Name: IAA carboxylmethyltransferase 1
Primary source: TAIR:AT5G55250
Locus tag: AT5G55250
See related: Araport:AT5G55250
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtIAMT1; IAA carboxylmethyltransferase 1; MCO15.20; MCO15_20
Summary: Encodes an enzyme which specifically converts IAA to its methyl ester form MelIAA. This gene belongs to the family of carboxyl methyltransferases whose members catalyze the transfer of the methyl group from S-adenosyl-L-methionine to carboxylic acid-containing substrates to form small molecule methyl esters. Expression of TCP genes is downregulated in mutant iamt1-D.
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Genomic context

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See IAMT1 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 4

Sequence:: Chromosome: 5; NC_003076.8 (22407427..22410974, complement)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Role of Arabidopsis INDOLE-3-ACETIC ACID CARBOXYL METHYLTRANSFERASE 1 in auxin metabolism.
Title: Role of Arabidopsis INDOLE-3-ACETIC ACID CARBOXYL METHYLTRANSFERASE 1 in auxin metabolism.
Data show that the expression of TCP4 and IAMT1 that encodes a methyltransferase converting free indole-3-acetic acid (IAA) to methyl-IAA ester (MeIAA) was induced and the induction level was dependent on the abundance of TaWRKY71-1 transcripts.
Title: Ectopic expression of a wheat WRKY transcription factor gene TaWRKY71-1 results in hyponastic leaves in Arabidopsis thaliana.
Indole-3-Acetic Acid Carboxyl Methyltransferase [IAMT1]is involved in Arabidopsis leaf development and has broad implications for auxin-regulated developmental processes.[IAMT1]
Title: An indole-3-acetic acid carboxyl methyltransferase regulates Arabidopsis leaf development.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001085287.2

Supported by ESTs:

NM_124907.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables S-adenosylmethionine-dependent methyltransferase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables indole acetic acid carboxyl methyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables indole-3-acetate carboxyl methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables magnesium ion binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in auxin biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within polarity specification of adaxial/abaxial axis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: IAA carboxylmethyltransferase 1

NP_001078756.1

IAA carboxylmethyltransferase 1 (IAMT1); CONTAINS InterPro DOMAIN/s: SAM dependent carboxyl methyltransferase (InterPro:IPR005299); BEST Arabidopsis thaliana protein match is: gibberellic acid methyltransferase 2 (TAIR:AT5G56300.1); Has 921 Blast hits to 905 proteins in 124 species: Archae - 0; Bacteria - 69; Metazoa - 9; Fungi - 5; Plants - 719; Viruses - 0; Other Eukaryotes - 119 (source: NCBI BLink).

NP_200336.1

IAA carboxylmethyltransferase 1 (IAMT1); CONTAINS InterPro DOMAIN/s: SAM dependent carboxyl methyltransferase (InterPro:IPR005299); BEST Arabidopsis thaliana protein match is: gibberellic acid methyltransferase 2 (TAIR:AT5G56300.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

22407427..22410974 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_124907.5 → NP_200336.1 IAA carboxylmethyltransferase 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_200336.1

Status: REVIEWED

UniProtKB/Swiss-Prot

A8MS18, Q56ZV4, Q8LAR1, Q9FLN8

UniProtKB/TrEMBL

A0A178UGG3, A0A5S9YER4, A0A654GBN2

Conserved Domains (1) summary

PLN02668
Location:1 → 386

PLN02668; indole-3-acetate carboxyl methyltransferase
NM_001085287.2 → NP_001078756.1 IAA carboxylmethyltransferase 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001078756.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A7G2FJD6

Conserved Domains (1) summary

cl04109
Location:1 → 348

Methyltransf_7; SAM dependent carboxyl methyltransferase