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    HDG11 homeodomain GLABROUS 11 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843671, updated on 31-Oct-2024

    Summary

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    Official Symbol
    HDG11
    Official Full Name
    homeodomain GLABROUS 11
    Primary source
    TAIR:AT1G73360
    Locus tag
    AT1G73360
    See related
    Araport:AT1G73360
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtEDT1; ATHDG11; EDT1; ENHANCED DROUGHT TOLERANCE 1; homeodomain GLABROUS 11; HOMEODOMAIN GLABROUS 11; T9L24.43; T9L24_43
    Summary
    Encodes a homeobox-leucine zipper family protein belonging to the HD-ZIP IV family. It is involved in trichome branching.
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    Genomic context

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    See HDG11 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Sequence:
    Chromosome: 1; NC_003070.9 (27578421..27582685, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ankyrin repeat protein Neighboring gene ncRNA Neighboring gene sucrose synthase 6 Neighboring gene uncharacterized protein Neighboring gene Endosomal targeting BRO1-like domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field. Yu LH, et al. Plant Biotechnol J, 2016 Jan. PMID 25879154, Free PMC Article
    2. Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis. Cai XT, et al. J Integr Plant Biol, 2015 Dec. PMID 25752924
    3. Activated expression of an Arabidopsis HD-START protein confers drought tolerance with improved root system and reduced stomatal density. Yu H, et al. Plant Cell, 2008 Apr. PMID 18451323, Free PMC Article
    4. HD-ZIP IV genes are essential for embryo initial cell polarization and the radial axis formation in Arabidopsis. Tanaka S, et al. Curr Biol, 2024 Oct 21. PMID 39303713
    5. BIL9 Promotes Both Plant Growth via BR Signaling and Drought Stress Resistance by Binding with the Transcription Factor HDG11. Surina S, et al. Plant Cell Physiol, 2024 Nov 13. PMID 38242155

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. HD-ZIP IV genes are essential for embryo initial cell polarization and the radial axis formation in Arabidopsis.
      Title: HD-ZIP IV genes are essential for embryo initial cell polarization and the radial axis formation in Arabidopsis.
    2. EDT1/HDG11-ERECTA-E2Fa genetic pathway that reduces stomatal density by increasing cell size and provide a new avenue to improve WUE of crops.
      Title: AtEDT1/HDG11 regulates stomatal density and water-use efficiency via ERECTA and E2Fa.
    3. AtHDG11 also confers drought and salt tolerance in upland cotton (Gossypium hirsutum) and woody plant poplar.
      Title: Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    4. overexpression of EDT1/HDG11 increases jasmonic acid level in the root of edt1D.
      Title: Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    5. directly upregulates cell-wall-loosening protein genes
      Title: HDG11 upregulates cell-wall-loosening protein genes to promote root elongation in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_105996.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_positive_effect cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within plant-type cell wall loosening IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within trichome branching IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within trichome branching IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    homeodomain GLABROUS 11
    NP_177479.1
    • homeodomain GLABROUS 11 (HDG11); CONTAINS InterPro DOMAIN/s: Homeobox, conserved site (InterPro:IPR017970), Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057), Lipid-binding START (InterPro:IPR002913), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: homeodomain GLABROUS 12 (TAIR:AT1G17920.1); Has 12070 Blast hits to 11936 proteins in 534 species: Archae - 0; Bacteria - 0; Metazoa - 9179; Fungi - 319; Plants - 2364; Viruses - 8; Other Eukaryotes - 200 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27578421..27582685 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105996.4 → NP_177479.1  homeodomain GLABROUS 11 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177479.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FX31
      UniProtKB/TrEMBL
      A0A178W9A4, A0A5S9WU15
      Conserved Domains (3) summary
      cd08875
      Location:231 → 456
      START_ArGLABRA2_like; C-terminal lipid-binding START domain of the Arabidopsis homeobox protein GLABRA 2 and related proteins
      pfam00046
      Location:35 → 88
      Homeobox; Homeobox domain
      cl14643
      Location:517 → 562
      SRPBCC; START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FX31.1

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