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    PIP5K1B phosphatidylinositol-4-phosphate 5-kinase type 1 beta [ Homo sapiens (human) ]

    Gene ID: 8395, updated on 10-Dec-2024

    Summary

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    Official Symbol
    PIP5K1Bprovided by HGNC
    Official Full Name
    phosphatidylinositol-4-phosphate 5-kinase type 1 betaprovided by HGNC
    Primary source
    HGNC:HGNC:8995
    See related
    Ensembl:ENSG00000107242 MIM:602745; AllianceGenome:HGNC:8995
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MSS4; STM7
    Summary
    Predicted to enable 1-phosphatidylinositol-4-phosphate 5-kinase activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Predicted to act upstream of or within phosphatidylinositol biosynthetic process. Located in uropod. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in colon (RPKM 8.2), duodenum (RPKM 7.6) and 20 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See PIP5K1B in Genome Data Viewer
    Location:
    9q21.11
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (68705240..69009176)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (80878758..81182716)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (71320156..71624092)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene TMEM252 divergent transcript Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:71231697-71232198 Neighboring gene uncharacterized LOC105376071 Neighboring gene dermatan sulfate epimerase pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19927 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28438 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19928 Neighboring gene NANOG hESC enhancer GRCh37_chr9:71283997-71284549 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:71319670-71320595 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28439 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28440 Neighboring gene ReSE screen-validated silencer GRCh37_chr9:71358945-71359139 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr9:71370585-71371135 Neighboring gene ReSE screen-validated silencer GRCh37_chr9:71394470-71394884 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:71394889-71395717 Neighboring gene adaptor related protein complex 3 subunit mu 2 pseudogene Neighboring gene PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr9:71440431-71440932 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28441 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr9:71487058-71487642 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28442 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr9:71546947-71548146 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr9:71561653-71562329 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:71564759-71565378 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:71565379-71565998 Neighboring gene uncharacterized LOC101927069 Neighboring gene RNA, U6 small nuclear 820, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28443 Neighboring gene Sharpr-MPRA regulatory region 10428 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28444 Neighboring gene CRISPRi-validated cis-regulatory element chr9.764 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19931 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28445 Neighboring gene Sharpr-MPRA regulatory region 187 Neighboring gene Friedreich ataxia repeat instability region Neighboring gene Sharpr-MPRA regulatory region 4997 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr9:71660286-71661281 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:71669749-71670250 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:71670251-71670750 Neighboring gene protein kinase cAMP-activated catalytic subunit gamma Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:71681521-71682120 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:71683371-71683870 Neighboring gene frataxin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Friedreich's ataxia: a defect in signal transduction? Carvajal JJ, et al. Hum Mol Genet, 1995 Aug. PMID 7581382
    2. Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movement. Lacalle RA, et al. J Cell Biol, 2007 Dec 31. PMID 18158329, Free PMC Article
    3. Cis-silencing of PIP5K1B evidenced in Friedreich's ataxia patient cells results in cytoskeleton anomalies. Bayot A, et al. Hum Mol Genet, 2013 Jul 15. PMID 23552101
    4. Type I phosphatidylinositol 4-phosphate 5-kinase homo- and heterodimerization determines its membrane localization and activity. Lacalle RA, et al. FASEB J, 2015 Jun. PMID 25713054
    5. Exon-intron structure of a 2.7-kb transcript of the STM7 gene with phosphatidylinositol-4-phosphate 5-kinase activity. Pook MA, et al. Genomics, 1997 May 15. PMID 9177790

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LRRC8A as a central mediator promotes colon cancer metastasis by regulating PIP5K1B/PIP2 pathway.
      Title: LRRC8A as a central mediator promotes colon cancer metastasis by regulating PIP5K1B/PIP2 pathway.
    2. Data indicate that type I phosphatidylinositol 4-phosphate 5-kinase PIP5KIbeta mutants whose dimerization was impaired showed a severe decrease in PI(4,5)P2 production and plasma membrane delocalization.
      Title: Type I phosphatidylinositol 4-phosphate 5-kinase homo- and heterodimerization determines its membrane localization and activity.
    3. Knockdown of PIP5K1B in fibroblasts reproduced abnormal actin cytoskeleton remodeling evidenced in Friedreich's ataxia patient cells.
      Title: Cis-silencing of PIP5K1B evidenced in Friedreich's ataxia patient cells results in cytoskeleton anomalies.
    4. Results identify PIPKIbeta as a novel regulator of focal adhesion disassembly and suggest that PIPKIbeta spatially regulates beta1 integrin endocytosis at adhesion sites to control cell migration.
      Title: Type I phosphatidylinositol phosphate kinase beta regulates focal adhesion disassembly by promoting beta1 integrin endocytosis.
    5. Results identify an isoform-specific PDZ-binding motif in PIP5KIbeta, which confers specificity for PIP5KIbeta signaling at the uropod during leukocyte chemotaxis.
      Title: An isoform-specific PDZ-binding motif targets type I PIP5 kinase beta to the uropod and controls polarization of neutrophil-like HL60 cells.
    6. Meta-analysis and genome-wide association study of gene-disease association. (HuGE Navigator)
      Title: New loci associated with kidney function and chronic kidney disease.
    7. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
      Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    8. Observational study and genome-wide association study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
      Title: Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches.
    9. Syk-dependent phosphorylation of PIP5K1B is the dominant modification responsible for the decrease in cellular phosphatidylinositol 4,5-bisphosphate.
      Title: Oxidative stress decreases phosphatidylinositol 4,5-bisphosphate levels by deactivating phosphatidylinositol- 4-phosphate 5-kinase beta in a Syk-dependent manner.
    10. findings show that the human type I phosphatidylinositol 4-phosphate 5-kinase isoform beta (PIPKIbeta) has a role in organizing signaling at the cell rear
      Title: Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movement.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study.
    EBI GWAS Catalog
    Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.
    EBI GWAS Catalog
    New loci associated with kidney function and chronic kidney disease.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-3-phosphate 5-kinase activity TAS
    Traceable Author Statement
    more info
    		  
    enables 1-phosphatidylinositol-4-phosphate 5-kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 1-phosphatidylinositol-4-phosphate 5-kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables 1-phosphatidylinositol-4-phosphate 5-kinase activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables 1-phosphatidylinositol-4-phosphate 5-kinase activity TAS
    Traceable Author Statement
    more info
    		  
    enables 1-phosphatidylinositol-5-kinase activity TAS
    Traceable Author Statement
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol kinase activity TAS
    Traceable Author Statement
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphatidylinositol biosynthetic process TAS
    Traceable Author Statement
    more info
    		  
    involved_in phosphatidylinositol phosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction TAS
    Traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    located_in endomembrane system IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in uropod IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylinositol 4-phosphate 5-kinase type-1 beta
    Names
    PIP5K1-beta
    PIP5KIbeta
    phosphatidylinositol 4-phosphate 5-kinase type I beta
    protein STM-7
    ptdIns(4)P-5-kinase 1 beta
    type I phosphatidylinositol 4-phosphate 5-kinase beta
    NP_001265182.1
    NP_001362965.1
    NP_001362966.1
    NP_001362968.1
    NP_001362969.1
    NP_001362970.1
    NP_003549.1
    XP_005252319.1
    XP_011517384.1
    XP_011517386.1
    XP_016870677.1
    XP_016870678.1
    XP_047279907.1
    XP_047279908.1
    XP_054219920.1
    XP_054219921.1
    XP_054219922.1
    XP_054219923.1
    XP_054219924.1
    XP_054219925.1
    XP_054219926.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001278253.2 → NP_001265182.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform 3

      See identical proteins and their annotated locations for NP_001265182.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and lacks an alternate exon in the 3' end, that causes a frameshift. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 2. Variants 3, 7 and 8 encode the same isoform.
      Source sequence(s)
      AK295587, AL354794, CB988216, CK299479
      Consensus CDS
      CCDS65063.1
      UniProtKB/Swiss-Prot
      O14986
      Related
      ENSP00000438082.1, ENST00000541509.5
      Conserved Domains (1) summary
      cd17307
      Location:27 → 400
      PIPKc_PIP5K1B; Phosphatidylinositol phosphate kinase (PIPK) catalytic domain found in phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1beta) and similar proteins

    2. NM_001376036.1 → NP_001362965.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL162730, AL354794, AL356219
      Consensus CDS
      CCDS6624.1
      UniProtKB/Swiss-Prot
      A8K9L9, B4DIG7, O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749
      Conserved Domains (1) summary
      cd17307
      Location:27 → 400
      PIPKc_PIP5K1B; Phosphatidylinositol phosphate kinase (PIPK) catalytic domain found in phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1beta) and similar proteins

    3. NM_001376037.1 → NP_001362966.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL162730, AL354794, AL356219
      Consensus CDS
      CCDS6624.1
      UniProtKB/Swiss-Prot
      A8K9L9, B4DIG7, O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749
      Conserved Domains (1) summary
      cd17307
      Location:27 → 400
      PIPKc_PIP5K1B; Phosphatidylinositol phosphate kinase (PIPK) catalytic domain found in phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1beta) and similar proteins

    4. NM_001376039.1 → NP_001362968.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL162730, AL354794, AL356219
      Consensus CDS
      CCDS6624.1
      UniProtKB/Swiss-Prot
      A8K9L9, B4DIG7, O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749
      Conserved Domains (1) summary
      cd17307
      Location:27 → 400
      PIPKc_PIP5K1B; Phosphatidylinositol phosphate kinase (PIPK) catalytic domain found in phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1beta) and similar proteins

    5. NM_001376040.1 → NP_001362969.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL162730, AL354794, AL356219
      Consensus CDS
      CCDS65063.1
      Conserved Domains (1) summary
      cd17307
      Location:27 → 400
      PIPKc_PIP5K1B; Phosphatidylinositol phosphate kinase (PIPK) catalytic domain found in phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1beta) and similar proteins

    6. NM_001376041.1 → NP_001362970.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL162730, AL354794, AL356219
      Consensus CDS
      CCDS65063.1
      Conserved Domains (1) summary
      cd17307
      Location:27 → 400
      PIPKc_PIP5K1B; Phosphatidylinositol phosphate kinase (PIPK) catalytic domain found in phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1beta) and similar proteins

    7. NM_003558.4 → NP_003549.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform 2

      See identical proteins and their annotated locations for NP_003549.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) represents the longer transcript and encodes the longer isoform (2). Variants 2, 4, 5 and 6 encode the same isoform.
      Source sequence(s)
      AK292734, AL354794, CB988216, CK299479, U78579
      Consensus CDS
      CCDS6624.1
      UniProtKB/Swiss-Prot
      A8K9L9, B4DIG7, O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749
      Related
      ENSP00000265382.2, ENST00000265382.8
      Conserved Domains (1) summary
      cd17307
      Location:27 → 400
      PIPKc_PIP5K1B; Phosphatidylinositol phosphate kinase (PIPK) catalytic domain found in phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1beta) and similar proteins

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

      Range
      68705240..69009176
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017015189.2 → XP_016870678.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

      UniProtKB/Swiss-Prot
      A8K9L9, B4DIG7, O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749
      Conserved Domains (1) summary
      cd17307
      Location:27 → 400
      PIPKc_PIP5K1B; Phosphatidylinositol phosphate kinase (PIPK) catalytic domain found in phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1beta) and similar proteins

    2. XM_047423951.1 → XP_047279907.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

      UniProtKB/Swiss-Prot
      A8K9L9, B4DIG7, O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749

    3. XM_047423952.1 → XP_047279908.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

      UniProtKB/Swiss-Prot
      A8K9L9, B4DIG7, O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749

    4. XM_017015188.2 → XP_016870677.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

      UniProtKB/Swiss-Prot
      A8K9L9, B4DIG7, O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749
      Conserved Domains (1) summary
      cd17307
      Location:27 → 400
      PIPKc_PIP5K1B; Phosphatidylinositol phosphate kinase (PIPK) catalytic domain found in phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1beta) and similar proteins

    5. XM_011519082.3 → XP_011517384.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

      See identical proteins and their annotated locations for XP_011517384.1

      UniProtKB/Swiss-Prot
      A8K9L9, B4DIG7, O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749
      Conserved Domains (1) summary
      cd17307
      Location:27 → 400
      PIPKc_PIP5K1B; Phosphatidylinositol phosphate kinase (PIPK) catalytic domain found in phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1beta) and similar proteins

    6. XM_011519084.4 → XP_011517386.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

      See identical proteins and their annotated locations for XP_011517386.1

      UniProtKB/Swiss-Prot
      A8K9L9, B4DIG7, O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749
      Conserved Domains (1) summary
      cd17307
      Location:27 → 400
      PIPKc_PIP5K1B; Phosphatidylinositol phosphate kinase (PIPK) catalytic domain found in phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1beta) and similar proteins

    7. XM_005252262.6 → XP_005252319.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

      See identical proteins and their annotated locations for XP_005252319.1

      UniProtKB/Swiss-Prot
      A8K9L9, B4DIG7, O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749
      Related
      ENSP00000435778.1, ENST00000478500.3
      Conserved Domains (1) summary
      cd17307
      Location:27 → 400
      PIPKc_PIP5K1B; Phosphatidylinositol phosphate kinase (PIPK) catalytic domain found in phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1beta) and similar proteins

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060933.1 Alternate T2T-CHM13v2.0

      Range
      80878758..81182716
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054363951.1 → XP_054219926.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

    2. XM_054363946.1 → XP_054219921.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

    3. XM_054363947.1 → XP_054219922.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

    4. XM_054363949.1 → XP_054219924.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

    5. XM_054363945.1 → XP_054219920.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

    6. XM_054363950.1 → XP_054219925.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

    7. XM_054363948.1 → XP_054219923.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001031687.1: Suppressed sequence

      Description
      NM_001031687.1: This RefSeq was permanently suppressed because there is insufficient support for the transcript and the protein and because the transcript is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O14986.2 GenPept UniProtKB/Swiss-Prot:O14986

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