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    Coa5 cytochrome C oxidase assembly factor 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 503252, updated on 9-Dec-2024

    Summary

    Official Symbol
    Coa5provided by RGD
    Official Full Name
    cytochrome C oxidase assembly factor 5provided by RGD
    Primary source
    RGD:1565095
    See related
    EnsemblRapid:ENSRNOG00000078514 AllianceGenome:RGD:1565095
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565095
    Summary
    Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to act upstream of or within leukocyte differentiation; spleen development; and thymus development. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 9. Orthologous to human COA5 (cytochrome c oxidase assembly factor 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 527.2), Kidney (RPKM 449.3) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Coa5 in Genome Data Viewer
    Location:
    9q21
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (47147267..47160724, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (39651459..39664870, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (44011471..44024876, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene CB1 cannabinoid receptor-interacting protein 1-like Neighboring gene inositol polyphosphate-4-phosphatase type I A Neighboring gene uncharacterized LOC120094669 Neighboring gene unc-50 inner nuclear membrane RNA binding protein Neighboring gene alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Neighboring gene CRACD like Neighboring gene uncharacterized LOC134480567

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    uncharacterized protein LOC503252

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195488.3NP_001182417.1  uncharacterized protein LOC503252

      See identical proteins and their annotated locations for NP_001182417.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A6INH0
      Related
      ENSRNOP00000104900.1, ENSRNOT00000156826.1
      Conserved Domains (1) summary
      pfam10203
      Location:1171
      Pet191_N; Cytochrome c oxidase assembly protein PET191

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      47147267..47160724 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063267658.1XP_063123728.1  uncharacterized protein LOC503252 isoform X1