Magee1 MAGE family member E1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Magee1provided by RGD
Official Full Name: MAGE family member E1provided by RGD
Primary source: RGD:1560259
See related: EnsemblRapid:ENSRNOG00000002660 AllianceGenome:RGD:1560259
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: DAMAGE; RGD1560259
Summary: Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in dendrite; perinuclear region of cytoplasm; and postsynaptic membrane. Predicted to be active in nucleus. Orthologous to human MAGEE1 (MAGE family member E1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: Xq22

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	X	NC_086039.1 (74254848..74258395)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	X	NC_051356.1 (70189242..70192789)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	X	NC_005120.4 (76083553..76087100)

Chromosome X - NC_086039.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in negative regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in dendrite	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in perinuclear region of cytoplasm	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
located_in postsynaptic membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: melanoma-associated antigen E1

Names: MAGE-E1 antigen; alpha-dystrobrevin-associated MAGE Protein; hepatocellular carcinoma-associated protein HCA1; melanoma antigen, family E, 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001079891.1 → NP_001073360.1 melanoma-associated antigen E1

See identical proteins and their annotated locations for NP_001073360.1

Status: PROVISIONAL

Source sequence(s)

BC128754

UniProtKB/Swiss-Prot

A1A5P9

Related

ENSRNOP00000054396.3, ENSRNOT00000003573.9

Conserved Domains (2) summary

PHA03249
Location:36 → 176

PHA03249; DNA packaging tegument protein UL25; Provisional

pfam01454
Location:474 → 642

MAGE; MAGE family