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    JAKMIP3 Janus kinase and microtubule interacting protein 3 [ Homo sapiens (human) ]

    Gene ID: 282973, updated on 10-Dec-2024

    Summary

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    Official Symbol
    JAKMIP3provided by HGNC
    Official Full Name
    Janus kinase and microtubule interacting protein 3provided by HGNC
    Primary source
    HGNC:HGNC:23523
    See related
    Ensembl:ENSG00000188385 MIM:611198; AllianceGenome:HGNC:23523
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    NECC2; Jamip3; C10orf14; C10orf39; bA140A10.5
    Summary
    Predicted to enable kinase binding activity and microtubule binding activity. Predicted to be located in Golgi apparatus and membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in brain (RPKM 2.2), prostate (RPKM 1.0) and 11 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See JAKMIP3 in Genome Data Viewer
    Location:
    10q26.3
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (132036364..132184858)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (132976652..133128086)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (133849868..133998362)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene protein phosphatase 2 regulatory subunit Bdelta Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:133785771-133786641 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:133794606-133795530 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2951 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2952 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:133809534-133810520 Neighboring gene uncharacterized LOC124902525 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:133820384-133820908 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:133823019-133823543 Neighboring gene BCL2 interacting protein 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:133832958-133833629 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:133842692-133843192 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:133852590-133853427 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:133857569-133858086 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:133858087-133858604 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:133878227-133878974 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:133881249-133881749 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_11218 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_11222 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_11225 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_11227 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:133920928-133921428 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:133933330-133934168 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:133934169-133935006 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:133951279-133951800 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:133956000-133956846 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:133955152-133955999 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:133959409-133959910 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:133959911-133960410 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:133960832-133961794 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:133977007-133977706 Neighboring gene JAKMIP3 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134001171-134001672 Neighboring gene dihydropyrimidinase like 4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4222 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134056390-134057274 Neighboring gene serine/threonine kinase 32C Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134067757-134068258 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134068259-134068758 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134078043-134078543 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134096746-134097345 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:134111356-134111519 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2953 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134122180-134122724 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134122725-134123267 Neighboring gene Sharpr-MPRA regulatory region 5064 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4223 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:134144980-134145514 Neighboring gene leucine rich repeat containing 27

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Jamip1 (marlin-1) defines a family of proteins interacting with janus kinases and microtubules. Steindler C, et al. J Biol Chem, 2004 Oct 8. PMID 15277531
    2. Identification and characterization of two novel (neuro)endocrine long coiled-coil proteins. Cruz-Garcia D, et al. FEBS Lett, 2007 Jul 10. PMID 17572408
    3. Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. Kim DK, et al. Am J Respir Crit Care Med, 2012 Dec 15. PMID 23144326, Free PMC Article
    4. Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma. Freire-Benéitez V, et al. NAR Cancer, 2021 Mar. PMID 34316702, Free PMC Article
    5. The DNA sequence and comparative analysis of human chromosome 10. Deloukas P, et al. Nature, 2004 May 27. PMID 15164054

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Observational study of gene-disease association. (HuGE Navigator)
      Title: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ37857, FLJ41432

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    janus kinase and microtubule-interacting protein 3
    Names
    neuroendocrine long coiled-coil 2
    neuroendocrine long coiled-coil protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105521.4 → NP_001098991.1  janus kinase and microtubule-interacting protein 3 isoform e

      See identical proteins and their annotated locations for NP_001098991.1

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS44494.1
      UniProtKB/Swiss-Prot
      A6PW00, Q5VZ66, Q69YM6, Q6ZT29
      UniProtKB/TrEMBL
      A0A590UJS0
      Related
      ENSP00000298622.4, ENST00000298622.9
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 818
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:430 → 625
      JAKMIP_CC3; JAKMIP CC3 domain

    2. NM_001323086.2 → NP_001310015.1  janus kinase and microtubule-interacting protein 3 isoform a

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS91379.1
      UniProtKB/TrEMBL
      A0A590UIU4, A0A590UJS0
      Related
      ENSP00000499222.1, ENST00000666210.1
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 831
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:430 → 625
      JAKMIP_CC3; JAKMIP CC3 domain

    3. NM_001323087.2 → NP_001310016.1  janus kinase and microtubule-interacting protein 3 isoform b

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS91378.1
      UniProtKB/TrEMBL
      A0A590UJH1, A0A590UJS0
      Related
      ENSP00000508932.1, ENST00000684848.1
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 820
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:430 → 625
      JAKMIP_CC3; JAKMIP CC3 domain

    4. NM_001323088.2 → NP_001310017.1  janus kinase and microtubule-interacting protein 3 isoform c

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      UniProtKB/TrEMBL
      A0A590UJS0

    5. NM_001323089.2 → NP_001310018.1  janus kinase and microtubule-interacting protein 3 isoform d

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS91381.1
      UniProtKB/TrEMBL
      A0A590UJT1, A0A590UK42
      Related
      ENSP00000499560.1, ENST00000657318.1

    6. NM_001323090.2 → NP_001310019.1  janus kinase and microtubule-interacting protein 3 isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) and variant 5 both encode the same isoform (e).
      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS44494.1
      UniProtKB/Swiss-Prot
      A6PW00, Q5VZ66, Q69YM6, Q6ZT29
      UniProtKB/TrEMBL
      A0A590UJS0
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 818
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:430 → 625
      JAKMIP_CC3; JAKMIP CC3 domain

    7. NM_001392039.1 → NP_001378968.1  janus kinase and microtubule-interacting protein 3 isoform f

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      UniProtKB/TrEMBL
      A0A590UJS0
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 835
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:428 → 623
      JAKMIP_CC3; JAKMIP CC3 domain

    8. NM_001392040.1 → NP_001378969.1  janus kinase and microtubule-interacting protein 3 isoform g

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      UniProtKB/TrEMBL
      A0A590UJS0
      Conserved Domains (2) summary
      TIGR02169
      Location:45 → 830
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam16034
      Location:430 → 625
      JAKMIP_CC3; JAKMIP CC3 domain

    9. NM_001392041.1 → NP_001378970.1  janus kinase and microtubule-interacting protein 3 isoform b

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS91378.1
      UniProtKB/TrEMBL
      A0A590UJH1, A0A590UJS0
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 820
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:430 → 625
      JAKMIP_CC3; JAKMIP CC3 domain

    10. NM_001392042.1 → NP_001378971.1  janus kinase and microtubule-interacting protein 3 isoform b

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS91378.1
      UniProtKB/TrEMBL
      A0A590UJH1, A0A590UJS0
      Related
      ENSP00000499416.1, ENST00000666974.1
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 820
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:430 → 625
      JAKMIP_CC3; JAKMIP CC3 domain

    11. NM_001392043.1 → NP_001378972.1  janus kinase and microtubule-interacting protein 3 isoform e

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS44494.1
      UniProtKB/Swiss-Prot
      A6PW00, Q5VZ66, Q69YM6, Q6ZT29
      UniProtKB/TrEMBL
      A0A590UJS0
      Related
      ENSP00000499753.1, ENST00000668452.1
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 818
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:430 → 625
      JAKMIP_CC3; JAKMIP CC3 domain

    12. NM_001392044.1 → NP_001378973.1  janus kinase and microtubule-interacting protein 3 isoform e

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS44494.1
      UniProtKB/Swiss-Prot
      A6PW00, Q5VZ66, Q69YM6, Q6ZT29
      UniProtKB/TrEMBL
      A0A590UJS0
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 818
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:430 → 625
      JAKMIP_CC3; JAKMIP CC3 domain

    13. NM_001392045.1 → NP_001378974.1  janus kinase and microtubule-interacting protein 3 isoform e

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS44494.1
      UniProtKB/Swiss-Prot
      A6PW00, Q5VZ66, Q69YM6, Q6ZT29
      UniProtKB/TrEMBL
      A0A590UJS0
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 818
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:430 → 625
      JAKMIP_CC3; JAKMIP CC3 domain

    14. NM_001392046.1 → NP_001378975.1  janus kinase and microtubule-interacting protein 3 isoform e

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS44494.1
      UniProtKB/Swiss-Prot
      A6PW00, Q5VZ66, Q69YM6, Q6ZT29
      UniProtKB/TrEMBL
      A0A590UJS0
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 818
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:430 → 625
      JAKMIP_CC3; JAKMIP CC3 domain

    15. NM_001392047.1 → NP_001378976.1  janus kinase and microtubule-interacting protein 3 isoform e

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS44494.1
      UniProtKB/Swiss-Prot
      A6PW00, Q5VZ66, Q69YM6, Q6ZT29
      UniProtKB/TrEMBL
      A0A590UJS0
      Related
      ENSP00000499375.1, ENST00000664697.1
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 818
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:430 → 625
      JAKMIP_CC3; JAKMIP CC3 domain

    16. NM_001392048.1 → NP_001378977.1  janus kinase and microtubule-interacting protein 3 isoform h

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      UniProtKB/TrEMBL
      A0A590UJS0
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 818
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:430 → 623
      JAKMIP_CC3; JAKMIP CC3 domain

    17. NM_001392049.1 → NP_001378978.1  janus kinase and microtubule-interacting protein 3 isoform h

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      UniProtKB/TrEMBL
      A0A590UJS0
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 818
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:430 → 623
      JAKMIP_CC3; JAKMIP CC3 domain

    18. NM_001392050.1 → NP_001378979.1  janus kinase and microtubule-interacting protein 3 isoform i

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      UniProtKB/TrEMBL
      A0A590UJS0
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 816
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:428 → 621
      JAKMIP_CC3; JAKMIP CC3 domain

    19. NM_001392051.1 → NP_001378980.1  janus kinase and microtubule-interacting protein 3 isoform j

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      UniProtKB/TrEMBL
      A0A590UJS0
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 815
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:427 → 622
      JAKMIP_CC3; JAKMIP CC3 domain

    20. NM_001392052.1 → NP_001378981.1  janus kinase and microtubule-interacting protein 3 isoform k

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS91380.1
      UniProtKB/TrEMBL
      A0A590UJ61, A0A590UJS0
      Related
      ENSP00000499285.1, ENST00000653512.1
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 809
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:428 → 623
      JAKMIP_CC3; JAKMIP CC3 domain

    21. NM_001392053.1 → NP_001378982.1  janus kinase and microtubule-interacting protein 3 isoform l

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      UniProtKB/TrEMBL
      A0A590UK42
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 765
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:358 → 551
      JAKMIP_CC3; JAKMIP CC3 domain

    22. NM_001392054.1 → NP_001378983.1  janus kinase and microtubule-interacting protein 3 isoform m

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      UniProtKB/TrEMBL
      A0A590UK42
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 748
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:358 → 553
      JAKMIP_CC3; JAKMIP CC3 domain

    23. NM_001392055.1 → NP_001378984.1  janus kinase and microtubule-interacting protein 3 isoform n

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS91382.1
      UniProtKB/TrEMBL
      A0A590UK42, A0A590UK98
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 746
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:358 → 553
      JAKMIP_CC3; JAKMIP CC3 domain

    24. NM_001392056.1 → NP_001378985.1  janus kinase and microtubule-interacting protein 3 isoform n

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS91382.1
      UniProtKB/TrEMBL
      A0A590UK42, A0A590UK98
      Related
      ENSP00000499788.1, ENST00000659050.1
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 746
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:358 → 553
      JAKMIP_CC3; JAKMIP CC3 domain

    25. NM_001392057.1 → NP_001378986.1  janus kinase and microtubule-interacting protein 3 isoform n

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS91382.1
      UniProtKB/TrEMBL
      A0A590UK42, A0A590UK98
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 746
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:358 → 553
      JAKMIP_CC3; JAKMIP CC3 domain

    26. NM_001392058.1 → NP_001378987.1  janus kinase and microtubule-interacting protein 3 isoform o

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      UniProtKB/TrEMBL
      A0A590UK42
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 745
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:355 → 550
      JAKMIP_CC3; JAKMIP CC3 domain

    27. NM_001392059.1 → NP_001378988.1  janus kinase and microtubule-interacting protein 3 isoform p

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS91383.1
      UniProtKB/TrEMBL
      A0A590UJC8, A0A590UK42
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 744
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:356 → 551
      JAKMIP_CC3; JAKMIP CC3 domain

    28. NM_001392060.1 → NP_001378989.1  janus kinase and microtubule-interacting protein 3 isoform p

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS91383.1
      UniProtKB/TrEMBL
      A0A590UJC8, A0A590UK42
      Related
      ENSP00000499227.1, ENST00000653623.1
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 744
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:356 → 551
      JAKMIP_CC3; JAKMIP CC3 domain

    29. NM_001392061.1 → NP_001378990.1  janus kinase and microtubule-interacting protein 3 isoform q

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS91385.1
      UniProtKB/TrEMBL
      A0A590UK11, A0A590UK42
      Related
      ENSP00000499650.1, ENST00000661339.1
      Conserved Domains (2) summary
      TIGR02168
      Location:55 → 734
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:347 → 542
      JAKMIP_CC3; JAKMIP CC3 domain

    30. NM_001392062.1 → NP_001378991.1  janus kinase and microtubule-interacting protein 3 isoform q

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS91385.1
      UniProtKB/TrEMBL
      A0A590UK11, A0A590UK42
      Related
      ENSP00000499348.1, ENST00000658847.1
      Conserved Domains (2) summary
      TIGR02168
      Location:55 → 734
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:347 → 542
      JAKMIP_CC3; JAKMIP CC3 domain

    31. NM_001392063.1 → NP_001378992.1  janus kinase and microtubule-interacting protein 3 isoform r

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      UniProtKB/TrEMBL
      A0A590UK42
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 732
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:358 → 553
      JAKMIP_CC3; JAKMIP CC3 domain

    32. NM_001392064.1 → NP_001378993.1  janus kinase and microtubule-interacting protein 3 isoform r

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      UniProtKB/TrEMBL
      A0A590UK42
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 732
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:358 → 553
      JAKMIP_CC3; JAKMIP CC3 domain

    33. NM_001392065.1 → NP_001378994.1  janus kinase and microtubule-interacting protein 3 isoform s

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS91384.1
      UniProtKB/TrEMBL
      A0A590UJG1, A0A590UK42
      Related
      ENSP00000499432.1, ENST00000669493.1
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 722
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:356 → 551
      JAKMIP_CC3; JAKMIP CC3 domain

    34. NM_001392066.1 → NP_001378995.1  janus kinase and microtubule-interacting protein 3 isoform t

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      UniProtKB/TrEMBL
      A0A590UK42
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 719
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:358 → 524
      JAKMIP_CC3; JAKMIP CC3 domain

    35. NM_001392067.1 → NP_001378996.1  janus kinase and microtubule-interacting protein 3 isoform u

      Status: VALIDATED

      Source sequence(s)
      AL162274, AL512622
      Consensus CDS
      CCDS91386.1
      UniProtKB/TrEMBL
      A0A590UJF4, A0A590UK42
      Related
      ENSP00000499400.1, ENST00000670443.1
      Conserved Domains (2) summary
      TIGR02168
      Location:1 → 660
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:273 → 468
      JAKMIP_CC3; JAKMIP CC3 domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      132036364..132184858
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011539676.3 → XP_011537978.1  janus kinase and microtubule-interacting protein 3 isoform X1

      See identical proteins and their annotated locations for XP_011537978.1

      UniProtKB/TrEMBL
      A0A590UIU4, A0A590UJS0
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 831
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:430 → 625
      JAKMIP_CC3; JAKMIP CC3 domain

    2. XM_047425106.1 → XP_047281062.1  janus kinase and microtubule-interacting protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A590UJS0

    3. XM_047425107.1 → XP_047281063.1  janus kinase and microtubule-interacting protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A590UJS0

    4. XM_047425109.1 → XP_047281065.1  janus kinase and microtubule-interacting protein 3 isoform X5

      UniProtKB/TrEMBL
      A0A590UJS0

    5. XM_017016095.3 → XP_016871584.1  janus kinase and microtubule-interacting protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A590UIU4, A0A590UJS0
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 831
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:430 → 625
      JAKMIP_CC3; JAKMIP CC3 domain

    6. XM_005252674.6 → XP_005252731.1  janus kinase and microtubule-interacting protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A590UJS0
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 830
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:430 → 625
      JAKMIP_CC3; JAKMIP CC3 domain

    7. XM_011539682.4 → XP_011537984.1  janus kinase and microtubule-interacting protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A590UJS0
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 759
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:358 → 553
      JAKMIP_CC3; JAKMIP CC3 domain

    8. XM_047425110.1 → XP_047281066.1  janus kinase and microtubule-interacting protein 3 isoform X6

      UniProtKB/TrEMBL
      A0A590UJS0

    9. XM_047425108.1 → XP_047281064.1  janus kinase and microtubule-interacting protein 3 isoform X4

      UniProtKB/TrEMBL
      A0A590UJS0

    10. XM_005252676.6 → XP_005252733.1  janus kinase and microtubule-interacting protein 3 isoform X5

      UniProtKB/TrEMBL
      A0A590UJS0
      Conserved Domains (2) summary
      TIGR02168
      Location:27 → 757
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:356 → 551
      JAKMIP_CC3; JAKMIP CC3 domain

    11. XM_047425111.1 → XP_047281067.1  janus kinase and microtubule-interacting protein 3 isoform X7

      UniProtKB/TrEMBL
      A0A590UK42

    12. XM_017016098.3 → XP_016871587.1  janus kinase and microtubule-interacting protein 3 isoform X8

    13. XM_017016099.3 → XP_016871588.1  janus kinase and microtubule-interacting protein 3 isoform X9

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      132976652..133128086
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054365628.1 → XP_054221603.1  janus kinase and microtubule-interacting protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A590UJS0

    2. XM_054365631.1 → XP_054221606.1  janus kinase and microtubule-interacting protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A590UJS0

    3. XM_054365633.1 → XP_054221608.1  janus kinase and microtubule-interacting protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A590UJS0

    4. XM_054365636.1 → XP_054221611.1  janus kinase and microtubule-interacting protein 3 isoform X5

      UniProtKB/TrEMBL
      A0A590UJS0

    5. XM_054365629.1 → XP_054221604.1  janus kinase and microtubule-interacting protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A590UJS0

    6. XM_054365630.1 → XP_054221605.1  janus kinase and microtubule-interacting protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A590UJS0

    7. XM_054365632.1 → XP_054221607.1  janus kinase and microtubule-interacting protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A590UJS0

    8. XM_054365637.1 → XP_054221612.1  janus kinase and microtubule-interacting protein 3 isoform X6

      UniProtKB/TrEMBL
      A0A590UJS0

    9. XM_054365634.1 → XP_054221609.1  janus kinase and microtubule-interacting protein 3 isoform X4

      UniProtKB/TrEMBL
      A0A590UJS0

    10. XM_054365635.1 → XP_054221610.1  janus kinase and microtubule-interacting protein 3 isoform X5

      UniProtKB/TrEMBL
      A0A590UJS0

    11. XM_054365638.1 → XP_054221613.1  janus kinase and microtubule-interacting protein 3 isoform X7

      UniProtKB/TrEMBL
      A0A590UK42

    12. XM_054365639.1 → XP_054221614.1  janus kinase and microtubule-interacting protein 3 isoform X9

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001104947.1: Suppressed sequence

      Description
      NM_001104947.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.

    2. NM_194303.1: Suppressed sequence

      Description
      NM_194303.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5VZ66.2 GenPept UniProtKB/Swiss-Prot:Q5VZ66

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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