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    Fam53a family with sequence similarity 53, member A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305461, updated on 27-Dec-2024

    Summary

    Official Symbol
    Fam53aprovided by RGD
    Official Full Name
    family with sequence similarity 53, member Aprovided by RGD
    Primary source
    RGD:1563315
    See related
    EnsemblRapid:ENSRNOG00000017548 AllianceGenome:RGD:1563315
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563315
    Summary
    Orthologous to human FAM53A (family with sequence similarity 53 member A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 82.6), Thymus (RPKM 55.6) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Fam53a in Genome Data Viewer
    Location:
    14q21
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (81308127..81348930)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (77088178..77124395)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (82375086..82416004)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene transforming, acidic coiled-coil containing protein 3 Neighboring gene transmembrane protein 129, E3 ubiquitin ligase Neighboring gene stem-loop histone mRNA binding protein Neighboring gene proteasome 20S subunit beta 3, pseudogene 5 Neighboring gene NK1 homeobox 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107228.2NP_001100698.1  protein FAM53A

      See identical proteins and their annotated locations for NP_001100698.1

      Status: PROVISIONAL

      Source sequence(s)
      BC168895
      UniProtKB/TrEMBL
      A6IK61, A6IK62, B5DF22
      Related
      ENSRNOP00000023904.4, ENSRNOT00000023904.7
      Conserved Domains (1) summary
      pfam15242
      Location:1299
      FAM53; Family of FAM53

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      81308127..81348930
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063273161.1XP_063129231.1  protein FAM53A isoform X1

      UniProtKB/TrEMBL
      A6IK61, A6IK62, B5DF22
    2. XM_063273156.1XP_063129226.1  protein FAM53A isoform X1

      UniProtKB/TrEMBL
      A6IK61, A6IK62, B5DF22
    3. XM_063273157.1XP_063129227.1  protein FAM53A isoform X1

      UniProtKB/TrEMBL
      A6IK61, A6IK62, B5DF22
    4. XM_063273155.1XP_063129225.1  protein FAM53A isoform X1

      UniProtKB/TrEMBL
      A6IK61, A6IK62, B5DF22
    5. XM_006251266.5XP_006251328.1  protein FAM53A isoform X1

      See identical proteins and their annotated locations for XP_006251328.1

      UniProtKB/TrEMBL
      A6IK61, A6IK62, B5DF22
      Conserved Domains (1) summary
      pfam15242
      Location:1299
      FAM53; Family of FAM53
    6. XM_063273162.1XP_063129232.1  protein FAM53A isoform X1

      UniProtKB/TrEMBL
      A6IK61, A6IK62, B5DF22
    7. XM_039091983.2XP_038947911.1  protein FAM53A isoform X1

      UniProtKB/TrEMBL
      A6IK61, A6IK62, B5DF22
      Conserved Domains (1) summary
      pfam15242
      Location:1299
      FAM53; Family of FAM53
    8. XM_063273160.1XP_063129230.1  protein FAM53A isoform X1

      UniProtKB/TrEMBL
      A6IK61, A6IK62, B5DF22
    9. XM_063273159.1XP_063129229.1  protein FAM53A isoform X1

      UniProtKB/TrEMBL
      A6IK61, A6IK62, B5DF22
    10. XM_039091982.2XP_038947910.1  protein FAM53A isoform X1

      UniProtKB/TrEMBL
      A6IK61, A6IK62, B5DF22
      Conserved Domains (1) summary
      pfam15242
      Location:1299
      FAM53; Family of FAM53
    11. XM_039091984.2XP_038947912.1  protein FAM53A isoform X2

      Conserved Domains (1) summary
      pfam15242
      Location:1299
      FAM53; Family of FAM53
    12. XM_006251262.5XP_006251324.1  protein FAM53A isoform X1

      See identical proteins and their annotated locations for XP_006251324.1

      UniProtKB/TrEMBL
      A6IK61, A6IK62, B5DF22
      Conserved Domains (1) summary
      pfam15242
      Location:1299
      FAM53; Family of FAM53
    13. XM_063273163.1XP_063129233.1  protein FAM53A isoform X2

    14. XM_006251268.5XP_006251330.1  protein FAM53A isoform X1

      See identical proteins and their annotated locations for XP_006251330.1

      UniProtKB/TrEMBL
      A6IK61, A6IK62, B5DF22
      Conserved Domains (1) summary
      pfam15242
      Location:1299
      FAM53; Family of FAM53
    15. XM_063273164.1XP_063129234.1  protein FAM53A isoform X3