ipo5.L importin 5 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: ipo5.L
Official Full Name: importin 5 L homeolog
Primary source: Xenbase:XB-GENE-6254154
Locus tag: XELAEV_18013132mg
See related: EnsemblRapid:ENSXLAG00005000599 AllianceGenome:Xenbase:XB-GENE-6254154
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: imb3; kpnb3; ipo5-a; ipo5-b; ranbp5; ranbp6
Summary: Predicted to enable small GTPase binding activity. Predicted to act upstream of or within protein import into nucleus. Predicted to be located in cytoplasm and nucleus. Is expressed in anatomical system; pharyngeal arch; and primary germ layer. Orthologous to human IPO5 (importin 5). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

Location:: chromosome: 2L

Exon count:: 26

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	2L	NC_054373.1 (126499753..126537832, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	2L	NC_030726.1 (120648799..120687320, complement)

Chromosome 2L - NC_054373.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables small GTPase binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein import into nucleus	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: importin 5 L homeolog

Names: RAN binding protein 5; kap beta 3; karyopherin-B3; karyopherin-beta 3; transporter

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001092945.1 → NP_001086414.1 importin 5 L homeolog

See identical proteins and their annotated locations for NP_001086414.1

Status: PROVISIONAL

Source sequence(s)

AF468651

UniProtKB/TrEMBL

A0A974HZC7, B7ZQB8, Q804V4

Related

ENSXLAP00005001671.1, ENSXLAT00005001712.1

Conserved Domains (3) summary

pfam13513
Location:369 → 423

HEAT_EZ; HEAT-like repeat

pfam13646
Location:356 → 464

HEAT_2; HEAT repeats

sd00044
Location:356 → 384

HEAT; HEAT repeat [structural motif]

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

126499753..126537832 complement

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GenBank, FASTA, Sequence Viewer (Graphics)