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    brd7.L bromodomain containing 7 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 398590, updated on 4-Jan-2025

    Summary

    Official Symbol
    brd7.L
    Official Full Name
    bromodomain containing 7 L homeolog
    Primary source
    Xenbase:XB-GENE-1017012
    Locus tag
    XELAEV_18022463mg
    See related
    EnsemblRapid:ENSXLAG00005006117 AllianceGenome:Xenbase:XB-GENE-1017012
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    brd7
    Summary
    Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human BRD7 (bromodomain containing 7). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

    See brd7.L in Genome Data Viewer
    Location:
    chromosome: 4L
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (39497024..39521210, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (36989701..37013987, complement)

    Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene terminal nucleotidyltransferase 4B L homeolog Neighboring gene adenylate cyclase 7 L homeolog Neighboring gene nucleoporin 93kDa L homeolog Neighboring gene uncharacterized LOC121403001

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    bromodomain-containing protein 7
    Names
    nuclear transcriptor-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001089123.1NP_001082592.1  bromodomain-containing protein 7

      See identical proteins and their annotated locations for NP_001082592.1

      Status: PROVISIONAL

      Source sequence(s)
      BC070751
      UniProtKB/TrEMBL
      A0A974D544, Q802C4
      Related
      ENSXLAP00005018362.1, ENSXLAT00005018659.1
      Conserved Domains (2) summary
      cd05513
      Location:138235
      Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
      pfam12024
      Location:289516
      DUF3512; Domain of unknown function (DUF3512)

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      39497024..39521210 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)