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    Tmem62 transmembrane protein 62 [ Mus musculus (house mouse) ]

    Gene ID: 96957, updated on 4-Jan-2025

    Summary

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    Official Symbol
    Tmem62provided by MGI
    Official Full Name
    transmembrane protein 62provided by MGI
    Primary source
    MGI:MGI:2139461
    See related
    Ensembl:ENSMUSG00000054484 AllianceGenome:MGI:2139461
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    B830009D23Rik
    Summary
    Predicted to enable hydrolase activity. Predicted to be located in membrane. Orthologous to human TMEM62 (transmembrane protein 62). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 12.0), adrenal adult (RPKM 5.8) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tmem62 in Genome Data Viewer
    Location:
    2 E5; 2 60.37 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (120806959..120838333)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (120976478..121007849)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene tau tubulin kinase 2 Neighboring gene STARR-seq mESC enhancer starr_05516 Neighboring gene STARR-positive B cell enhancer ABC_E3396 Neighboring gene expressed sequence AV039307 Neighboring gene ubiquitin protein ligase E3 component n-recognin 1 Neighboring gene STARR-positive B cell enhancer ABC_E5971 Neighboring gene STARR-positive B cell enhancer ABC_E147 Neighboring gene small nucleolar RNA, C/D box 3B, pseudogene 2 Neighboring gene cyclin D-type binding-protein 1 Neighboring gene erythrocyte membrane protein band 4.2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs. Pan J, et al. Am J Reprod Immunol, 2015 Sep. PMID 26073538
    2. Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each. Dogar AM, et al. PLoS One, 2018. PMID 30418981, Free PMC Article
    3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    4. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    5. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 62

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175285.4 → NP_780494.1  transmembrane protein 62

      Status: VALIDATED

      Source sequence(s)
      AL844548
      Consensus CDS
      CCDS16629.1
      UniProtKB/Swiss-Prot
      A2AQ55, Q8BXJ9
      Related
      ENSMUSP00000064310.8, ENSMUST00000067582.14
      Conserved Domains (2) summary
      COG1409
      Location:59 → 260
      CpdA; 3',5'-cyclic AMP phosphodiesterase CpdA [Signal transduction mechanisms]
      cd07401
      Location:57 → 345
      MPP_TMEM62_N; Homo sapiens TMEM62, N-terminal metallophosphatase domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      120806959..120838333
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030252259.2 → XP_030108119.1  transmembrane protein 62 isoform X1

      UniProtKB/TrEMBL
      A2AQ56
      Related
      ENSMUSP00000106314.3, ENSMUST00000110686.3
      Conserved Domains (2) summary
      pfam17957
      Location:208 → 259
      Big_7; Bacterial Ig domain
      cl13995
      Location:28 → 213
      MPP_superfamily; metallophosphatase superfamily, metallophosphatase domain

    RNA

    1. XR_374546.3 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BXJ9.1 GenPept UniProtKB/Swiss-Prot:Q8BXJ9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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