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    1700018B08Rik RIKEN cDNA 1700018B08 gene [ Mus musculus (house mouse) ]

    Gene ID: 76405, updated on 27-Nov-2024

    Summary

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    Official Symbol
    1700018B08Rikprovided by MGI
    Official Full Name
    RIKEN cDNA 1700018B08 geneprovided by MGI
    Primary source
    MGI:MGI:1923655
    See related
    Ensembl:ENSMUSG00000031809 AllianceGenome:MGI:1923655
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700084O22Rik
    Summary
    Orthologous to human C16orf95 (chromosome 16 open reading frame 95). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 90.3) See more
    Orthologs
    human all
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    Genomic context

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    See 1700018B08Rik in Genome Data Viewer
    Location:
    8 E1; 8 70.64 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (122257515..122271077, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (121530776..121544339, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 26747 Neighboring gene predicted gene, 53465 Neighboring gene RIKEN cDNA 1700030M09 gene Neighboring gene F-box protein 31 Neighboring gene STARR-positive B cell enhancer ABC_E2276

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein C16orf95 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357259.1 → NP_001344188.1  uncharacterized protein C16orf95 homolog isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in the 5' coding region and initiates translation at an alternate start codon compared to variant 1. The encoded isoform (2) has a distinct, shorter N-terminus than isoform 1.
      Source sequence(s)
      AC122205, AK006079, BC172077
      Conserved Domains (1) summary
      pfam15132
      Location:23 → 208
      DUF4568; Domain of unknown function (DUF4568)

    2. NM_001357260.1 → NP_001344189.1  uncharacterized protein C16orf95 homolog isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses two alternate splice sites in the 5' region and initiates translation at a downstream start codon compared to variant 1. The encoded isoform (3) has a shorter N-terminus than isoform 1.
      Source sequence(s)
      AC122205, AK006079, BC172082
      Conserved Domains (1) summary
      pfam15132
      Location:1 → 136
      DUF4568; Domain of unknown function (DUF4568)

    3. NM_001382230.1 → NP_001369159.1  uncharacterized protein C16orf95 homolog isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC122205
      UniProtKB/TrEMBL
      S4R173
      Conserved Domains (1) summary
      pfam15132
      Location:30 → 227
      DUF4568; Domain of unknown function (DUF4568)

    4. NM_001382231.1 → NP_001369160.1  uncharacterized protein C16orf95 homolog isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC122205
      UniProtKB/TrEMBL
      S4R173
      Related
      ENSMUSP00000138106.2, ENSMUST00000182460.2
      Conserved Domains (1) summary
      pfam15132
      Location:30 → 227
      DUF4568; Domain of unknown function (DUF4568)

    5. NM_001382232.1 → NP_001369161.1  uncharacterized protein C16orf95 homolog isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC122205
      UniProtKB/TrEMBL
      S4R173
      Conserved Domains (1) summary
      pfam15132
      Location:30 → 227
      DUF4568; Domain of unknown function (DUF4568)

    6. NM_001382233.1 → NP_001369162.1  uncharacterized protein C16orf95 homolog isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC122205
      UniProtKB/TrEMBL
      S4R173
      Conserved Domains (1) summary
      pfam15132
      Location:30 → 227
      DUF4568; Domain of unknown function (DUF4568)

    7. NM_029597.2 → NP_083873.1  uncharacterized protein C16orf95 homolog isoform 1

      See identical proteins and their annotated locations for NP_083873.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform 1.
      Source sequence(s)
      AK006079, BY448457
      Consensus CDS
      CCDS52692.1
      UniProtKB/TrEMBL
      Q9DA83
      Related
      ENSMUSP00000034265.4, ENSMUST00000034265.11
      Conserved Domains (1) summary
      pfam15132
      Location:26 → 213
      DUF4568; Domain of unknown function (DUF4568)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      122257515..122271077 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011248543.3 → XP_011246845.1  uncharacterized protein C16orf95 homolog isoform X3

      Conserved Domains (1) summary
      pfam15132
      Location:1 → 186
      DUF4568; Domain of unknown function (DUF4568)

    2. XM_006531475.4 → XP_006531538.1  uncharacterized protein C16orf95 homolog isoform X2

      Conserved Domains (1) summary
      pfam15132
      Location:30 → 227
      DUF4568; Domain of unknown function (DUF4568)

    3. XM_006531474.4 → XP_006531537.1  uncharacterized protein C16orf95 homolog isoform X1

      Conserved Domains (1) summary
      pfam15132
      Location:52 → 249
      DUF4568; Domain of unknown function (DUF4568)
    Nucleotide Protein Strain
    Heading Accession and Version

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