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    Btf3l4 basic transcription factor 3-like 4 [ Mus musculus (house mouse) ]

    Gene ID: 70533, updated on 3-Dec-2024

    Summary

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    Official Symbol
    Btf3l4provided by MGI
    Official Full Name
    basic transcription factor 3-like 4provided by MGI
    Primary source
    MGI:MGI:1915312
    See related
    Ensembl:ENSMUSG00000028568 AllianceGenome:MGI:1915312
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4632412E09Rik; 5730434I03Rik
    Summary
    Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human BTF3L4 (basic transcription factor 3 like 4). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E14 (RPKM 19.6), whole brain E14.5 (RPKM 19.2) and 23 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Btf3l4 in Genome Data Viewer
    Location:
    4 C7; 4 50.64 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (108671489..108691445, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (108814295..108834302, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene zinc finger, FYVE domain containing 9 Neighboring gene ribosomal protein L9 pseudogene Neighboring gene predicted gene, 53266 Neighboring gene STARR-seq mESC enhancer starr_11051 Neighboring gene STARR-seq mESC enhancer starr_11052 Neighboring gene STARR-positive B cell enhancer mm9_chr4:108520274-108520575 Neighboring gene thioredoxin domain containing 12 (endoplasmic reticulum) Neighboring gene KTI12 homolog, chromatin associated Neighboring gene RAB3B, member RAS oncogene family Neighboring gene STARR-seq mESC enhancer starr_11058 Neighboring gene RIKEN cDNA 8030443G20 gene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set. VanBuren V, et al. Genome Res, 2002 Dec. PMID 12466305, Free PMC Article
    2. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
    3. Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies. Murtaza N, et al. Cell Rep, 2022 Nov 22. PMID 36417873
    4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    5. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    transcription factor BTF3 homolog 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356361.2 → NP_001343290.1  transcription factor BTF3 homolog 4 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AL607070
      Consensus CDS
      CCDS18456.1
      UniProtKB/Swiss-Prot
      Q9CQH7
      UniProtKB/TrEMBL
      A2A7Z4, Q78IG7
      Conserved Domains (1) summary
      cd22055
      Location:4 → 120
      NAC_BTF3; basal transcription factor BTF3

    2. NM_001404469.1 → NP_001391398.1  transcription factor BTF3 homolog 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL607070
      UniProtKB/Swiss-Prot
      Q9CQH7
      UniProtKB/TrEMBL
      A2A7Z4, Q78IG7

    3. NM_001404470.1 → NP_001391399.1  transcription factor BTF3 homolog 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL607070
      UniProtKB/Swiss-Prot
      Q9CQH7
      UniProtKB/TrEMBL
      A2A7Z4, Q78IG7
      Related
      ENSMUSP00000099802.2, ENSMUST00000102741.8

    4. NM_001404471.1 → NP_001391400.1  transcription factor BTF3 homolog 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL607070
      UniProtKB/Swiss-Prot
      Q9CQH7
      UniProtKB/TrEMBL
      A2A7Z4, Q78IG7

    5. NM_001404472.1 → NP_001391401.1  transcription factor BTF3 homolog 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL607070
      UniProtKB/Swiss-Prot
      Q9CQH7
      UniProtKB/TrEMBL
      A2A7Z4, Q78IG7
      Related
      ENSMUSP00000099801.2, ENSMUST00000102740.8

    6. NM_001404473.1 → NP_001391402.1  transcription factor BTF3 homolog 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL607070
      UniProtKB/Swiss-Prot
      Q9CQH7
      UniProtKB/TrEMBL
      A2A7Z4, Q78IG7
      Related
      ENSMUSP00000099800.2, ENSMUST00000102739.2

    7. NM_001404474.1 → NP_001391403.1  transcription factor BTF3 homolog 4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL607070
      UniProtKB/TrEMBL
      Q78IG7

    8. NM_001404475.1 → NP_001391404.1  transcription factor BTF3 homolog 4 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL607070
      UniProtKB/TrEMBL
      Q78IG7

    9. NM_001404476.1 → NP_001391405.1  transcription factor BTF3 homolog 4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL607070
      UniProtKB/TrEMBL
      Q78IG7

    10. NM_001404477.1 → NP_001391406.1  transcription factor BTF3 homolog 4 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL607070
      UniProtKB/TrEMBL
      Q78IG7

    11. NM_001404478.1 → NP_001391407.1  transcription factor BTF3 homolog 4 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AL607070

    12. NM_001404479.1 → NP_001391408.1  transcription factor BTF3 homolog 4 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AL607070

    13. NM_001404480.1 → NP_001391409.1  transcription factor BTF3 homolog 4 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL607070

    14. NM_001404481.1 → NP_001391410.1  transcription factor BTF3 homolog 4 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL607070

    15. NM_001404482.1 → NP_001391411.1  transcription factor BTF3 homolog 4 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AL607070

    16. NM_001404483.1 → NP_001391412.1  transcription factor BTF3 homolog 4 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL607070

    17. NM_001404484.1 → NP_001391413.1  transcription factor BTF3 homolog 4 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL607070

    18. NM_001404486.1 → NP_001391415.1  transcription factor BTF3 homolog 4 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL607070

    19. NM_001404487.1 → NP_001391416.1  transcription factor BTF3 homolog 4 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL607070

    20. NM_001404488.1 → NP_001391417.1  transcription factor BTF3 homolog 4 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL607070

    21. NM_001404489.1 → NP_001391418.1  transcription factor BTF3 homolog 4 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL607070

    22. NM_027453.4 → NP_081729.1  transcription factor BTF3 homolog 4 isoform 1

      See identical proteins and their annotated locations for NP_081729.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AL607070
      Consensus CDS
      CCDS18456.1
      UniProtKB/Swiss-Prot
      Q9CQH7
      UniProtKB/TrEMBL
      A2A7Z4, Q78IG7
      Related
      ENSMUSP00000099803.5, ENSMUST00000102742.11
      Conserved Domains (1) summary
      cd22055
      Location:4 → 120
      NAC_BTF3; basal transcription factor BTF3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      108671489..108691445 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CQH7.1 GenPept UniProtKB/Swiss-Prot:Q9CQH7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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