U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PERK4 roline-rich extensin-like receptor kinase 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816362, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    PERK4
    Official Full Name
    roline-rich extensin-like receptor kinase 4
    Primary source
    TAIR:AT2G18470
    Locus tag
    AT2G18470
    See related
    Araport:AT2G18470
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtPERK4; proline-rich extensin-like receptor kinase 4; roline-rich extensin-like receptor kinase 4; T30D6.2
    Summary
    Proline-rich extensin-like receptor kinase 4. Functions at an early stage of ABA signalling inhibiting primary root cell elongation by perturbing Ca2+ homeostasis.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PERK4 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Sequence:
    Chromosome: 2; NC_003071.7 (8005003..8008681, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene succinate dehydrogenase 1-2 Neighboring gene uncharacterized protein Neighboring gene Chaperone DnaJ-domain superfamily protein Neighboring gene Major facilitator superfamily protein Neighboring gene miscRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Plasma membrane-associated proline-rich extensin-like receptor kinase 4, a novel regulator of Ca signalling, is required for abscisic acid responses in Arabidopsis thaliana. Bai L, et al. Plant J, 2009 Oct. PMID 19566594
    2. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PERK4 localised to the plasma membrane, and was shown to be an ABA- and Ca(2+)-activated protein kinase.
      Title: Plasma membrane-associated proline-rich extensin-like receptor kinase 4, a novel regulator of Ca signalling, is required for abscisic acid responses in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    NM_001335595.1
    NM_001335596.1
    NM_001335597.1
    NM_127403.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within abscisic acid-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within calcium-mediated signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within seed germination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    roline-rich extensin-like receptor kinase 4
    NP_179437.1
    • roline-rich extensin-like receptor kinase 4 (PERK4); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: proline extensin-like receptor kinase 1 (TAIR:AT3G24550.1); Has 204492 Blast hits to 156803 proteins in 5113 species: Archae - 274; Bacteria - 30506; Metazoa - 74357; Fungi - 20978; Plants - 40817; Viruses - 2896; Other Eukaryotes - 34664 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      8005003..8008681 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127403.3 → NP_179437.1  roline-rich extensin-like receptor kinase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179437.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZNQ8
      Conserved Domains (2) summary
      smart00219
      Location:290 → 556
      TyrKc; Tyrosine kinase, catalytic domain
      cl21453
      Location:290 → 558
      PKc_like; Protein Kinases, catalytic domain

    2. NM_001335595.1 → NP_001324512.1  roline-rich extensin-like receptor kinase 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZNQ8

    3. NM_001335596.1 → NP_001324511.1  roline-rich extensin-like receptor kinase 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZNQ8

    4. NM_001335597.1 → NP_001324513.1  roline-rich extensin-like receptor kinase 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B0D2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZNQ8.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.