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    cactus-binding carboxy-terminal, cactin [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839371, updated on 18-Sep-2024

    Summary

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    Official Full Name
    cactus-binding carboxy-terminal, cactin
    Primary source
    TAIR:AT1G03910
    Locus tag
    AT1G03910
    See related
    Araport:AT1G03910
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CACTIN; CTN; F21M11.16; F21M11_16
    Summary
    Encodes the Arabidopsis homolog of a conserved eukaryotic protein without known functional domains. The protein that localizes to nuclear speckles and colocalizes with known splicing proteins.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    14
    Sequence:
    Chromosome: 1; NC_003070.9 (996076..1000629)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene non-intrinsic ABC protein 4 Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene Protein kinase family protein Neighboring gene dual specificity kinase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CACTIN is an essential nuclear protein in Arabidopsis and may be associated with the eukaryotic spliceosome. Baldwin KL, et al. FEBS Lett, 2013 Apr 2. PMID 23454656
    2. Arabidopsis ACINUS is O-glycosylated and regulates transcription and alternative splicing of regulators of reproductive transitions. Bi Y, et al. Nat Commun, 2021 Feb 11. PMID 33574257, Free PMC Article
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that CACTIN is required for embryogenesis.
      Title: CACTIN is an essential nuclear protein in Arabidopsis and may be associated with the eukaryotic spliceosome.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001197975.1
    NM_100272.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    cactus-binding carboxy-terminal, cactin
    NP_001184904.1
    • EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cactin protein, cactus-binding domain, C-terminal (InterPro:IPR019134), Cactin, central region (InterPro:IPR018816); BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT2G36815.2).
    NP_171887.1
    • EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cactin protein, cactus-binding domain, C-terminal (InterPro:IPR019134), Cactin, central region (InterPro:IPR018816); BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT2G36815.2); Has 11711 Blast hits to 7382 proteins in 452 species: Archae - 31; Bacteria - 352; Metazoa - 6006; Fungi - 1138; Plants - 599; Viruses - 33; Other Eukaryotes - 3552 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      996076..1000629
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100272.4 → NP_171887.1  cactus-binding carboxy-terminal, cactin [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_171887.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WHR8, A0A5S9SGA3, A0A7G2DSM6
      Conserved Domains (2) summary
      pfam09732
      Location:548 → 672
      CactinC_cactus; Cactus-binding C-terminus of cactin protein
      pfam10312
      Location:194 → 391
      Cactin_mid; Conserved mid region of cactin

    2. NM_001197975.1 → NP_001184904.1  cactus-binding carboxy-terminal, cactin [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001184904.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4I2J8, Q9ZWB1
      UniProtKB/TrEMBL
      A0A7G2DSM6
      Conserved Domains (2) summary
      pfam09732
      Location:592 → 716
      CactinC_cactus; Cactus-binding C-terminus of cactin protein
      pfam10312
      Location:194 → 433
      Cactin_mid; Conserved mid region of cactin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4I2J8.1

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