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    RABG3B RAB GTPase homolog G3B [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838880, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RABG3B
    Official Full Name
    RAB GTPase homolog G3B
    Primary source
    TAIR:AT1G22740
    Locus tag
    AT1G22740
    See related
    Araport:AT1G22740
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATRABG3B; RAB GTPase homolog G3B; RAB GTPase homolog G3B; RAB7; RAB75; T22J18.9; T22J18_9
    Summary
    GTP-binding protein Rab7
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    Genomic context

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    See RABG3B in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Sequence:
    Chromosome: 1; NC_003070.9 (8049090..8050784)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Protein kinase superfamily protein Neighboring gene MA3 domain-containing protein Neighboring gene uncharacterized protein Neighboring gene poly(A) binding protein 3 Neighboring gene gigantea protein (GI)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Rab GTPase RabG3b positively regulates autophagy and immunity-associated hypersensitive cell death in Arabidopsis. Kwon SI, et al. Plant Physiol, 2013 Apr. PMID 23404918, Free PMC Article
    2. Role of Arabidopsis RabG3b and autophagy in tracheary element differentiation. Kwon SI, et al. Autophagy, 2010 Nov. PMID 20861670
    3. The Rab GTPase RabG3b functions in autophagy and contributes to tracheary element differentiation in Arabidopsis. Kwon SI, et al. Plant J, 2010 Oct. PMID 20659276
    4. Sequence analysis of a 24-kb contiguous genomic region at the Arabidopsis thaliana PFL locus on chromosome 1. Terryn N, et al. FEBS Lett, 1997 Oct 20. PMID 9369203
    5. Qualitative difference between "bulb" membranes and other vacuolar membranes. Saito C, et al. Plant Signal Behav, 2011 Dec. PMID 22105033, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. VHA-a3 targets to the tonoplast through a Rab5-mediated but Rab7-independent pathway, shedding new lights on the unconventional vacuolar trafficking route in plant cells.[Rab7]
      Title: Tonoplast targeting of VHA-a3 relies on a Rab5-mediated but Rab7-independent vacuolar trafficking route.
    2. Hypersensitive response cell death via the activation of autophagy, which plays a positive role in plant immunity-triggered hypersensitive response programmed cell death.
      Title: The Rab GTPase RabG3b positively regulates autophagy and immunity-associated hypersensitive cell death in Arabidopsis.
    3. Vam3 is more concentrated than GFP-AtRab75 in the vacuolar bulb membrane.
      Title: Qualitative difference between "bulb" membranes and other vacuolar membranes.
    4. RabG3b functions as a component of autophagy and regulates tracheary elements differentiation by activating the process of programmed cell death.
      Title: Role of Arabidopsis RabG3b and autophagy in tracheary element differentiation.
    5. RabG3b plays a positive role in tracheary elements differentiation by activating autophagy.
      Title: The Rab GTPase RabG3b functions in autophagy and contributes to tracheary element differentiation in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_102121.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of autophagy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of autophagy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within programmed cell death involved in cell development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within tracheary element differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in xylem development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    located_in plant-type vacuole HDA PubMed 

    General protein information

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    Preferred Names
    RAB GTPase homolog G3B
    NP_173688.1
    • RAB GTPase homolog G3B (RABG3B); FUNCTIONS IN: GTP binding; INVOLVED IN: intracellular protein transport, signal transduction, nucleocytoplasmic transport, protein transport, small GTPase mediated signal transduction; LOCATED IN: vacuole; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Ran GTPase (InterPro:IPR002041), Ras (InterPro:IPR013753), Ras small GTPase, Ras type (InterPro:IPR003577), Small GTPase, Rho type (InterPro:IPR003578), Small GTP-binding protein (InterPro:IPR005225), Ras GTPase (InterPro:IPR001806), Small GTPase (InterPro:IPR020851), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: RAB GTPase homolog G3A (TAIR:AT4G09720.1); Has 25691 Blast hits to 25666 proteins in 724 species: Archae - 21; Bacteria - 135; Metazoa - 13533; Fungi - 3489; Plants - 2837; Viruses - 20; Other Eukaryotes - 5656 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      8049090..8050784
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102121.3 → NP_173688.1  RAB GTPase homolog G3B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173688.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04157, Q2HIJ2
      UniProtKB/TrEMBL
      A0A178WGP7, A0A5S9VK05
      Conserved Domains (1) summary
      cd01862
      Location:9 → 180
      Rab7; Rab GTPase family 7 (Rab7)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O04157.1

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