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    DPMS1 Nucleotide-diphospho-sugar transferases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838646, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DPMS1
    Official Full Name
    Nucleotide-diphospho-sugar transferases superfamily protein
    Primary source
    TAIR:AT1G20575
    Locus tag
    AT1G20575
    See related
    Araport:AT1G20575
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    dolichol phosphate mannose synthase 1
    Summary
    Encodes the catalytic core of the dolichol phosphate mannase synthase (DPMS) complex. It is not active on its own but requires the presence of DPMS2 and DPMS3 for full activity. It is localized in the ER and mediates isoprenyl-linked glycan biogenesis, influences development, stress response, and ammonium hypersensitivity.
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    Genomic context

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    See DPMS1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (7126747..7128762, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene O-fucosyltransferase family protein Neighboring gene acyl activating enzyme 1 Neighboring gene Spc97 / Spc98 family of spindle pole body (SBP) component Neighboring gene Small nuclear ribonucleoprotein family protein Neighboring gene cyclin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DOLICHOL PHOSPHATE MANNOSE SYNTHASE1 mediates the biogenesis of isoprenyl-linked glycans and influences development, stress response, and ammonium hypersensitivity in Arabidopsis. Jadid N, et al. Plant Cell, 2011 May. PMID 21558543, Free PMC Article
    2. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. In plants, Dol-P-Man is synthesized when Dol-P-Man synthase1 (DPMS1), the catalytic core, interacts with two binding proteins, DPMS2 and DPMS3, that may serve as membrane anchors for DPMS1 or provide catalytic assistance.
      Title: DOLICHOL PHOSPHATE MANNOSE SYNTHASE1 mediates the biogenesis of isoprenyl-linked glycans and influences development, stress response, and ammonium hypersensitivity in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_101908.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    contributes_to dolichyl-phosphate beta-D-mannosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in dolichol metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in dolichol-linked oligosaccharide biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein O-linked mannosylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within response to ammonium ion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of dolichol-phosphate-mannose synthase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Nucleotide-diphospho-sugar transferases superfamily protein
    NP_564118.1
    • Nucleotide-diphospho-sugar transferases superfamily protein; CONTAINS InterPro DOMAIN/s: Glycosyl transferase, family 2 (InterPro:IPR001173); BEST Arabidopsis thaliana protein match is: Nucleotide-diphospho-sugar transferases superfamily protein (TAIR:AT2G39630.1); Has 22705 Blast hits to 22656 proteins in 2589 species: Archae - 933; Bacteria - 16103; Metazoa - 288; Fungi - 260; Plants - 98; Viruses - 23; Other Eukaryotes - 5000 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      7126747..7128762 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101908.4 → NP_564118.1  Nucleotide-diphospho-sugar transferases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564118.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LDI9, Q9LM93
      UniProtKB/TrEMBL
      A0A178WDF9, A0A5S9VCC2, A0A654EBJ2
      Conserved Domains (1) summary
      PLN02726
      Location:5 → 246
      PLN02726; dolichyl-phosphate beta-D-mannosyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LM93.1

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